NBDC Research ID: hum0580.v1
SUMMARY
Aims: The Keio Women's Health Biobank aims to collect and store patient specimens and to appropriately provide specimens and clinical information for future studies. In addition, the biobank seeks to establish a research infrastructure that controbutes to medical reseraches by providing gynecologic tumor organoids (three-dimensionally cultured cells derived from normal / diseased tissues) together with clinical information, multi-omics data, and drug sensitivity testing information to academic institutions and pharmaceutical companies in Japan and abroad.
Methods: whole genome sequencing
Participants/Materials: a patient with gastric-type cervical adenocarcinoma
| Dataset ID | Type of Data | Criteria | Release Date |
|---|---|---|---|
| JGAS000796 | NGS (WGS) | Controlled-access (Type I) | 2026/05/20 |
* Data users need to apply an application for Using NBDC Human Data to reach the Controlled-access Data. Learn more
MOLECULAR DATA
| Participants/Materials |
gastric-type cervical adenocarcinoma (ICD10: C539): 1 case tumor tissue: 2 samples tumor organoid derived from patient's tumor tissues: 2 samples normal tissue (PBMC): 1 sample |
| Targets | WGS |
| Target Loci for Capture Methods | - |
| Platform | Illumina [NovaSeq 6000] |
| Library Source | DNAs extracted from tumor tissues, tumor organoids and normal tissue |
| Cell Lines | - |
| Library Construction (kit name) | NovaSeq 6000 S4 Reagent Kit v1.5 |
| Fragmentation Methods | Ultrasonic fragmentation |
| Spot Type | Paired-end |
| Read Length (without Barcodes, Adaptors, Primers, and Linkers) | 150 bp |
| Japanese Genotype-phenotype Archive Dataset ID | JGAD000938 |
| Total Data Volume | 386.7 GB (fastq) |
| Comments (Policies) | NBDC policy |
DATA PROVIDER
Principal Investigator: Masaki Sugawara
Affiliation: Department of Obstetrics and Gynecology, Keio University School of Medicine
Project / Group Name: -
Funds / Grants (Research Project Number):
| Name | Title | Project Number |
|---|---|---|
| KAKENHI Grant-in-Aid for Scientific Research (C) | Development of a Novel Culture Method to Enhance Antitumor Activity in Tumor-Infiltrating Lymphocyte Therapy | 24K12609 |
PUBLICATIONS
| Title | DOI | Dataset ID | |
|---|---|---|---|
| 1 | Establishment and genomic characterization of patient-derived organoids from gastric-type cervical adenocarcinoma | doi: 10.3802/jgo.2026.37.e101 | JGAD000938 |
| 2 |
USRES (Controlled-access Data)
| Principal Investigator | Affiliation | Country/Region | Research Title | Data in Use (Dataset ID) | Period of Data Use |
|---|---|---|---|---|---|
