NBDC Research ID: hum0137.v1
SUMMARY
Aims: To identify susceptibility genes to type 1 diabetes
Methods: NGS (Target Capture)
Participants/Materials: Type 1 diabetes
| Dataset ID | Type of Data | Criteria | Release Date |
|---|---|---|---|
| JGAS000144 | NGS (Target Capture) | Controlled-access (Type I) | 2018/12/21 |
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MOLECULAR DATA
| Participants/Materials | Type 1 diabetes (ICD10: E10): 32 cases |
| Targets | Target Capture |
| Target Loci for Capture Methods |
1. chr.12: 53,551,446-53,574,693 2. chr.12: 53,585,106-53,601,000 |
| Platform | Thermo Fisher Scientific [Ion Proton] |
| Library Source | DNAs extracted from peripheral blood cells |
| Cell Lines | - |
| Library Construction (kit name) | Amplicon Sequencing |
| Fragmentation Methods | Enzymatic fragmentation |
| Spot Type | Single-end |
| Read Length (without Barcodes, Adaptors, Primers, and Linkers) | 151 bp |
| Japanese Genotype-phenotype Archive Dataset ID | JGAD000213 |
| Total Data Volume | 21 GB (fastq) |
| Comments (Policies) | NBDC policy |
DATA PROVIDER
Principal Investigator: Hiroshi Ikegami
Affiliation: Department of Endocrinology, Metabolism and Diabetes Kinkdai University Faculty of Medicine
Project / Group Name: Core member for genetic analysis in the committee on type 1 diabetes, Japan Diabetes Society.
Funds / Grants (Research Project Number):
| Name | Title | Project Number |
|---|---|---|
| - |
PUBLICATIONS
| Title | DOI | Dataset ID | |
|---|---|---|---|
| 1 | A genome-wide association study confirming a strong effect of HLA and identifying variants in CSAD/lnc-ITGB7-1 on chromosome 12q13.13 associated with susceptibility to fulminant type 1 diabetes | doi: 10.2337/db18-0314 | JGAD000213 |
| 2 |
USRES (Controlled-access Data)
| Principal Investigator: | Affiliation: | Data in Use (Dataset ID) | Period of Data Use |
|---|---|---|---|
