NBDC Research ID: hum0113.v1

SUMMARY

Aims: Identification of RNA biomarkers in Parkinson's disease (PD) patients

Methods: Transcriptome sequencing (CAGE-seq)

Participants/Materials: Whole blood samples from 39 PD patients and 20 non-PD (healthy) contorols

Dataset ID	Type of Data	Criteria	Release Date
JGAS000119	NGS (CAGE-seq)	Controlled-access (Type I)	2020/04/24

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MOLECULAR DATA


Participants/Materials	39 PD patients (ICD10: G20) and 20 non-PD (healthy) contorols
Targets	CAGE-seq
Target Loci for Capture Methods	-
Platform	Illumina [HiSeq 2500]
Library Source	RNA extracted from whole blood
Cell Lines	-
Library Construction (kit name)	nAnT-iCAGE protocol (PMID: 24927836)
Fragmentation Methods	-
Spot Type	Single-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers)	47-50 bp
Japanese Genotype-phenotype Archive Dataset ID	JGAD000129
Total Data Volume	35 GB (fastq)
Comments (Policies)	NBDC policy

Principal Investigator: Piero Carninci

Affiliation: RIKEN Center for Integrative Medicine Science, Division of Genomic Medicine

Project / Group Name:-

Funds / Grants (Research Project Number):

Name	Title	Project Number
Core Research and Evolutional Science and Technology, Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED-CREST)	Development of metabolite biomarker specific for Parkinson's disease and identification of drug seeds based on its molecular target	JP19gm0710011

	Title	DOI	Dataset ID
1	Multi-year whole-blood transcriptome data for the study of onset and progression of Parkinson’s Disease	doi: 10.1038/s41597-019-0022-9	JGAD000129
2

Principal Investigator:	Affiliation:	Data in Use (Dataset ID)	Period of Data Use