NBDC Research ID: hum0021.v1

SUMMARY

Aims: Identify genes relevant to bipolar disorder

Methods: Whole exome sequence analysis using Illumina HiSeq 2000

Participants/Materials: Three pairs of healthy monozygotic twins

Data Set ID	Type of Data	Criteria	Release Date
JGAS000014	NGS (Exome)	Controlled Access (Type I)	2015/01/26

*Release Note

* Data users need to apply an application for Using NBDC Human Data to reach the Controlled-access Data.

MOLECULAR DATA

JGAS000014


Participants/Materials	Three pairs of healthy monozygotic twins
Targets	Exome
Target Loci for Capture Methods	-
Platform	Illumina [HiSeq 2000]
Library Source	gDNA extracted from peripheral blood cells
Cell Lines	-
Library Construction (kit name)	SureSelect Human All Exon 50 Mb Kit (Agilent)
Fragmentation Methods	Ultrasonic fragmentation (Covaris S220)
Spot Type	Paired-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers)	100 bp
Japanese Genotype-phenotype Archive Data set ID	JGAD000014
Total Data Volume	118 GB
Comments (Policies)	NBDC policy

This study was supported by “Genome Science”. “Genome Science” is a part of the “Support Programs for Three Fields in Life Sciences (cancer, genome and brain sciences)” established by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) under the Grant-in-Aid for Scientific Research on Innovative Areas.

DATA PROVIDER

Principal Investigator: Tadafumi Kato

Affiliation: RIKEN Brain Science Institute

Project / Group Name: Laboratory of Molecular Dynamics of Mental Disorders

URL： http://mdmd.riken.jp/en/

Funds / Grants (Research Project Number):

Name	Title	Project Number
KAKENHI Grant-in-Aid for Challenging Exploratory Research	Search for genetic mutations by next generation sequencing of monozygotic twins discordant for bipolar disorder.	21659277

PUBLICATIONS

	Title	DOI	Data Set ID
1
2

USERS (Controlled-Access Data)

Principal Investigator:	Affiliation:	Data in Use (Data Set ID)	Period of Data Use