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We are currently receiving a large number of applications for data submission, and the review process is taking longer than usual.We sincerely apologize for the delay and kindly ask for your understanding. When submitting an application, we would greatly appreciate it if you could allow sufficient time for the processing.

Following a change to our organizational structure effective April 1, 2026, this division has been renamed from the "Database Center for Life Science, Joint Support-Center for Data Science Research" to the "Database Division for Life Science (DBCLS), BioData Science Initiative (BSI), National Institute of Genetics (NIG)". Where the former name still appears in the guidelines, please read it as the new name.

Dataset ID

NHA000203

Type of data
Genome-wide gene-environment interaction studies for clinical traits and metabolites (374 phenotypes)
Access criteria
Unrestricted-access
Total data volume
1.2 TB
File formats
  • TXT
  • XLSX
Research
hum0197
Date published
2025-10-27
Date modified
2025-10-27
Secondary ID
hum0197.v26.374-traits.v1

Unrestricted-access files linked to this dataset

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101–200 / 8930

FileLabelSizeCopy URL
BBJ1.clinical.BUN.European_cuisine.txt.gz392 MB
BBJ1.clinical.BUN.Ever_drinking.txt.gz392 MB
BBJ1.clinical.BUN.Ever_smoking.txt.gz392 MB
BBJ1.clinical.BUN.Japanese_cuisine_Washoku.txt.gz393 MB
BBJ1.clinical.BUN.Joint_all_environments.txt.gz1.2 GB
BBJ1.clinical.BUN.Joint_commonly_tested_environments.txt.gz804 MB
BBJ1.clinical.BUN.Physical_activity.txt.gz393 MB
BBJ1.clinical.BUN.Sex.txt.gz392 MB
BBJ1.clinical.CAD.Age.txt.gz394 MB
BBJ1.clinical.CAD.Combined.txt.gz230 MB
BBJ1.clinical.CAD.Current_smoking.txt.gz394 MB
BBJ1.clinical.CAD.Dairy_products.txt.gz394 MB
BBJ1.clinical.CAD.European_cuisine.txt.gz393 MB
BBJ1.clinical.CAD.Ever_drinking.txt.gz394 MB
BBJ1.clinical.CAD.Ever_smoking.txt.gz394 MB
BBJ1.clinical.CAD.Japanese_cuisine_Washoku.txt.gz394 MB
BBJ1.clinical.CAD.Joint_all_environments.txt.gz1.2 GB
BBJ1.clinical.CAD.Joint_commonly_tested_environments.txt.gz806 MB
BBJ1.clinical.CAD.Physical_activity.txt.gz394 MB
BBJ1.clinical.CAD.Sex.txt.gz394 MB
BBJ1.clinical.CRP.Age.txt.gz394 MB
BBJ1.clinical.CRP.Combined.txt.gz230 MB
BBJ1.clinical.CRP.Current_smoking.txt.gz394 MB
BBJ1.clinical.CRP.Dairy_products.txt.gz394 MB
BBJ1.clinical.CRP.European_cuisine.txt.gz394 MB
BBJ1.clinical.CRP.Ever_drinking.txt.gz394 MB
BBJ1.clinical.CRP.Ever_smoking.txt.gz394 MB
BBJ1.clinical.CRP.Japanese_cuisine_Washoku.txt.gz394 MB
BBJ1.clinical.CRP.Joint_all_environments.txt.gz1.2 GB
BBJ1.clinical.CRP.Joint_commonly_tested_environments.txt.gz808 MB
BBJ1.clinical.CRP.Physical_activity.txt.gz394 MB
BBJ1.clinical.CRP.Sex.txt.gz394 MB
BBJ1.clinical.Ca.Age.txt.gz396 MB
BBJ1.clinical.Ca.Combined.txt.gz230 MB
BBJ1.clinical.Ca.Current_smoking.txt.gz396 MB
BBJ1.clinical.Ca.Dairy_products.txt.gz396 MB
BBJ1.clinical.Ca.European_cuisine.txt.gz396 MB
BBJ1.clinical.Ca.Ever_drinking.txt.gz396 MB
BBJ1.clinical.Ca.Ever_smoking.txt.gz396 MB
BBJ1.clinical.Ca.Japanese_cuisine_Washoku.txt.gz396 MB
BBJ1.clinical.Ca.Joint_all_environments.txt.gz1.2 GB
BBJ1.clinical.Ca.Joint_commonly_tested_environments.txt.gz813 MB
BBJ1.clinical.Ca.Physical_activity.txt.gz396 MB
BBJ1.clinical.Ca.Sex.txt.gz396 MB
BBJ1.clinical.Cataract.Age.txt.gz394 MB
BBJ1.clinical.Cataract.Combined.txt.gz230 MB
BBJ1.clinical.Cataract.Current_smoking.txt.gz394 MB
BBJ1.clinical.Cataract.Dairy_products.txt.gz394 MB
BBJ1.clinical.Cataract.European_cuisine.txt.gz393 MB
BBJ1.clinical.Cataract.Ever_drinking.txt.gz394 MB
BBJ1.clinical.Cataract.Ever_smoking.txt.gz394 MB
BBJ1.clinical.Cataract.Japanese_cuisine_Washoku.txt.gz394 MB
BBJ1.clinical.Cataract.Joint_all_environments.txt.gz1.2 GB
BBJ1.clinical.Cataract.Joint_commonly_tested_environments.txt.gz807 MB
BBJ1.clinical.Cataract.Physical_activity.txt.gz394 MB
BBJ1.clinical.Cataract.Sex.txt.gz394 MB
BBJ1.clinical.DBP.Age.txt.gz391 MB
BBJ1.clinical.DBP.Combined.txt.gz230 MB
BBJ1.clinical.DBP.Current_smoking.txt.gz391 MB
BBJ1.clinical.DBP.Dairy_products.txt.gz392 MB
BBJ1.clinical.DBP.European_cuisine.txt.gz391 MB
BBJ1.clinical.DBP.Ever_drinking.txt.gz391 MB
BBJ1.clinical.DBP.Ever_smoking.txt.gz391 MB
BBJ1.clinical.DBP.Japanese_cuisine_Washoku.txt.gz392 MB
BBJ1.clinical.DBP.Joint_all_environments.txt.gz1.2 GB
BBJ1.clinical.DBP.Joint_commonly_tested_environments.txt.gz799 MB
BBJ1.clinical.DBP.Physical_activity.txt.gz392 MB
BBJ1.clinical.DBP.Sex.txt.gz391 MB
BBJ1.clinical.Dyslipidemia.Age.txt.gz394 MB
BBJ1.clinical.Dyslipidemia.Combined.txt.gz230 MB
BBJ1.clinical.Dyslipidemia.Current_smoking.txt.gz394 MB
BBJ1.clinical.Dyslipidemia.Dairy_products.txt.gz395 MB
BBJ1.clinical.Dyslipidemia.European_cuisine.txt.gz394 MB
BBJ1.clinical.Dyslipidemia.Ever_drinking.txt.gz394 MB
BBJ1.clinical.Dyslipidemia.Ever_smoking.txt.gz394 MB
BBJ1.clinical.Dyslipidemia.Japanese_cuisine_Washoku.txt.gz395 MB
BBJ1.clinical.Dyslipidemia.Joint_all_environments.txt.gz1.2 GB
BBJ1.clinical.Dyslipidemia.Joint_commonly_tested_environments.txt.gz808 MB
BBJ1.clinical.Dyslipidemia.Physical_activity.txt.gz395 MB
BBJ1.clinical.Dyslipidemia.Sex.txt.gz394 MB
BBJ1.clinical.Eosino.Age.txt.gz394 MB
BBJ1.clinical.Eosino.Combined.txt.gz230 MB
BBJ1.clinical.Eosino.Current_smoking.txt.gz394 MB
BBJ1.clinical.Eosino.Dairy_products.txt.gz395 MB
BBJ1.clinical.Eosino.European_cuisine.txt.gz394 MB
BBJ1.clinical.Eosino.Ever_drinking.txt.gz394 MB
BBJ1.clinical.Eosino.Ever_smoking.txt.gz394 MB
BBJ1.clinical.Eosino.Japanese_cuisine_Washoku.txt.gz395 MB
BBJ1.clinical.Eosino.Joint_all_environments.txt.gz1.2 GB
BBJ1.clinical.Eosino.Joint_commonly_tested_environments.txt.gz809 MB
BBJ1.clinical.Eosino.Physical_activity.txt.gz395 MB
BBJ1.clinical.Eosino.Sex.txt.gz394 MB
BBJ1.clinical.GGT.Age.txt.gz396 MB
BBJ1.clinical.GGT.Combined.txt.gz230 MB
BBJ1.clinical.GGT.Current_smoking.txt.gz396 MB
BBJ1.clinical.GGT.Dairy_products.txt.gz397 MB
BBJ1.clinical.GGT.European_cuisine.txt.gz396 MB
BBJ1.clinical.GGT.Ever_drinking.txt.gz397 MB
BBJ1.clinical.GGT.Ever_smoking.txt.gz397 MB
BBJ1.clinical.GGT.Japanese_cuisine_Washoku.txt.gz397 MB

101–200 / 8930

Analysis method

genome wide SNPs

Materials and participants
BioBank Japan (n=166,757), UK Biobank (n=273,453)
(ICD 10: E11, I20, I21, I22, I23, I24, I25, I44, I45, I46, I47, I48, I49, E78, I60, I61, I62, I63, I64, H25, H26, H28, J45, J46, N20, N21, N22, J30.2)
no. Phenotypes: 374
  • Health status
    Mixed
  • Subject count
    440,210 (Individual)
  • Cohort
    BioBank Japan, UK Biobank
  • Population
    British, Japanese
Disease
  • Type 2 diabetes mellitus
Sample description
DNAs extracted from peripheral blood cells
  • Tissue
    Peripheral blood
  • Tumor / normal
    Normal
Sample provider
N/A
Experimental method
Genotyping by array
Target
N/A
Reagent kit
HumanExome BeadChip Kit
HumanOmniExpress BeadChip Kit
HumanOmniExpressExome BeadChip Kit
UK BiLEVE Axiom Array
UK Biobank Axiom Array
Platform
Applied Biosystems UK BiLEVE Axiom Array
Applied Biosystems UK Biobank Axiom Array
Illumina HumanExome
Illumina HumanOmniExpress
Illumina HumanOmniExpressExome
QC and filtering
Clinical Phenotypes: imputation quality > 0.7, minor allele frequency (MAF) > 0.01, autosomal variants
Metabolome: further restricted to (i) genotyped variants, (ii) HapMap3 variants, and (iii) the variants with P_G×E < 1.0×10^-7 in BBJ or UKBB for at least one of the clinical traits
Imputation
BBJ: Eagle, Minimac3
UK Biobank: IMPUTE4
Analysis method
GEM
Variant count
BBJ: 7,444,735 (Clinical traits)
1,009,566 (Metabolome)
UK Biobank: 9,813,264 (Clinical traits)
1,478,430 (Metabolome)
Phenotype data
Included
Data use policy
NBDC data sharing policy (JGAP000001)