NBDC Research ID: hum0223.v1
SUMMARY
Aims: To clarify of the disease status of myeloma and lymphoma by somatic gene mutation analyses
Methods: gene mutaion analyses using NGS technology at the point of diagnosis, relapse, or proceeding disease
Participants/Materials: multiple myeloma
Dataset ID | Type of Data | Criteria | Release Date |
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JGAS000232 | NGS (Target Capture) | Controlled-access (Type I) | 2020/09/01 |
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MOLECULAR DATA
Participants/Materials |
multiple myeloma (ICD10: C90.0): 7 cases myeloma cells from bone marrow aspirates: total 30 samples |
Targets | Target Capture |
Target Loci for Capture Methods | 126 genes |
Platform | Thermo Fisher Scientific [Ion Proton] |
Library Source | DNAs extracted from myeloma cells isolated from bone marrow samples at the point of diagnosis, relapse, or proceeding disease |
Cell Lines | - |
Library Construction (kit name) | Ion Ampliseq Designer™ |
Fragmentation Methods | - |
Spot Type | Single-end |
Read Length (without Barcodes, Adaptors, Primers, and Linkers) | 3-1754 bp |
QC/Filtering Methods | TaqMan® Assay |
Deduplication | - |
Mapping Methods | TMAP |
Reference Genome Sequence | hg19 |
Coverage (Depth) | 2815 |
Detecting Methods for Variation) | Variant Caller |
Japanese Genotype-phenotype Archive Dataset ID | JGAD000326 |
Total Data Volume | 87 GB(vcf) |
Comments (Policies) | NBDC policy |
DATA PROVIDER
Principal Investigator: Yasuhito Terui
Affiliation: Dept of Hematology Oncology, The Cancer Institute Hospital of JFCR
Project / Group Name: -
Funds / Grants (Research Project Number):
Name | Title | Project Number |
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- |
PUBLICATIONS
Title | DOI | Dataset ID | |
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1 | The clonal evolution during long-term clinical course of multiple myeloma | doi: 10.1007/s12185-020-02979-7 | JGAD000326 |
2 |
USRES (Controlled-access Data)
Principal Investigator | Affiliation | Country/Region | Research Title | Data in Use (Dataset ID) | Period of Data Use |
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