NBDC Research ID: hum0197.v1

SUMMARY

Aims: Elucidation of gut microbiome’s role in human biology

Methods: A comprehensive metagenome-wide association study by utilizing whole-genome shotgun sequencing

Participants/Materials: Metagenomic data of gut microbiome in the Japanese population

Data Set ID	Type of Data	Criteria	Release Date
JGAS000205	Metagenome	Controlled Access (Type I)	2019/11/15

* Data users need to apply an application for Using NBDC Human Data to reach the Controlled-access Data.

MOLECULAR DATA


Participants/Materials:	95 Japanese individuals
Targets	Metagenome
Target Loci for Capture Methods	-
Platform	Illumina [HiSeq 3000]
Library Source	DNA extracted from gut microbiome
Cell Lines	-
Library Construction (kit name)	KAPA Hyper Prep Kit
Fragmentation Methods	Ultrasonic fragmentation (Covaris)
Spot Type	Paired-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers)	150 bp
Japanese Genotype-phenotype Archive Data set ID	JGAD000290
Total Data Volume	477 GB (fastq)
Comments (Policies)	NBDC policy

Principal Investigator: Yukinori Okada

Affiliation: Department of Statistical Genetics, Osaka University Graduate School of Medicine

Project / Group Name： -

Funds / Grants (Research Project Number):

Name	Title	Project Number
Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED-PRIME)	Crosstalk among microbiome, host, disease, and drug discovery enhanced by statistical genetics	19gm6010001h0004

	Title	DOI	Data Set ID
1	Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population.	doi: 10.1136/annrheumdis-2019-215743	JGAD000290
2

Principal Investigator:	Affiliation:	Data in Use (Data Set ID)	Period of Data Use