NBDC Research ID: hum0184.v1
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SUMMARY
Aims: Tohoku University Tohoku Medical Megabank Organization (ToMMo) and Iwate Tohoku Medical Megabank Organization (IMM) were founded to establish an advanced medical system to foster the reconstruction from the Great East Japan Earthquake. These organizations are developing a biobank that includes medical and genome information for supporting health and welfare in the Tohoku area. In the first stage, the part of our mission was to sequence the 4,000 individuals to construct Japanese whole-genome reference panel.
Methods: Whole genome sequencing
Participants/Materials: 4,566 Japanese general residents
URL： https://jmorp.megabank.tohoku.ac.jp/
| Data Set ID | Type of Data | Criteria | Release Date |
|---|---|---|---|
| JGAS000239 | NGS (WGS) | Controlled Access (Type II) | 2020/09/01 |
* Data users need to apply an application for Using NBDC Human Data to reach the Controlled-access Data.
MOLECULAR DATA
| Participants/Materials: | 4,566 Japanese general residents |
| Targets | WGS |
| Target Loci for Capture Methods | - |
| Platform | Illumina [HiSeq 2500, NovaSeq 6000] |
| Library Source | DNA extracted from peripheral blood cells |
| Cell Lines | - |
| Library Construction (kit name) | TruSeq DNA PCR-Free Library Prep Kit |
| Fragmentation Methods | Ultrasonic fragmentation (Covaris LE220) |
| Spot Type | Paired-end |
| Read Length (without Barcodes, Adaptors, Primers, and Linkers) |
HiSeq 2500: 162 bp / 259 bp NovaSeq 6000: 150 bp |
| Japanese Genotype-phenotype Archive Data set ID | |
| Total Data Volume |
JGAD000338: 260 TB (fastq) JGAD000339: 230 TB (bam, gvcf, vcf [ref: GRCh37/hg19 (hs37d5)]) |
| Comments (Policies) |
DATA PROVIDER
Principal Investigator: Masayuki Yamamoto
Affiliation: Tohoku Medical Megabank Organization
Project / Group Name： Tohoku Medical Megabank Project
URL： https://www.megabank.tohoku.ac.jp/english/
Funds / Grants (Research Project Number):
| Name | Title | Project Number |
|---|---|---|
| Japan Agency for Medical Research and Development (AMED) | Tohoku Medical Megabank Project (Tohoku University) Special Account of the Great East Japan Earthquake Disaster Recovery | JP20km0105001 |
| Japan Agency for Medical Research and Development (AMED) | Tohoku Medical Megabank Project (Tohoku University) General Accounting | JP20km0105002 |
| Japan Agency for Medical Research and Development (AMED) | Tohoku Medical Megabank Project (Iwate Medical University) Special Account of the Great East Japan Earthquake Disaster Recovery | JP20km0105003 |
| Japan Agency for Medical Research and Development (AMED) | Tohoku Medical Megabank Project (Iwate Medical University) General Accounting | JP20km0105004 |
PUBLICATIONS
| Title | DOI | Data Set ID | |
|---|---|---|---|
| 1 | 3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome | doi: 10.1038/s41439-019-0059-5 | hum0015.v3.3.5kjpnv2.v1 |
| 2 |
USRES (Controlled-Access Data)
| Principal Investigator: | Affiliation: | Data in Use (Data Set ID) | Period of Data Use |
|---|---|---|---|
