NBDC Research ID: hum0134.v1

 

SUMMARY

Aims: Identification of molecular targets for development effective therapeutic methods and genomic or epigenomic markers for stratification of B cell lymphoma patients.

Methods: Exome analysis by using of Illumina HiSeq 2000

Participants/Materials: 147 normal, primary tumor, and recurrent tumor samples from 60 B cell lymphoma patients

 

Dataset IDType of DataCriteriaRelease Date
JGAS000087
NGS (Exome) Controlled-access (Type I) 2018/04/06

*Release Note

*Data users need to apply an application for Using NBDC Human Data to reach the Controlled-access Data. Learn more

 

MOLECULAR DATA

JGAS000087

Participants/Materials

B cell lymphoma: 60 cases (Total: 147 samples)

   non-tumor tissue: 60 samples

   tumor tissue (metastasis/recurrence): 87 samples

Targets Exome
Target Loci for Capture Methods -
Platform Illumina [HiSeq 2000]
Library Source DNAs extracted from tumor and non-tumor tissues from 60 B cell lymphoma patients
Cell Lines -
Library Construction (kit name) SureSelect Human All Exon V4 + lincRNA, SureSelect Human All Exon V5 + lincRNA
Fragmentation Methods Ultrasonic fragmentation (Covaris E220)
Spot Type Paired-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers) 100 bp
Japanese Genotype-phenotype Archive Dataset ID JGAD000087
Total Data Volume 3 TB (fastq [294 files])
Comments (Policies) NBDC policy

 

DATA PROVIDER

Principal Investigator: Toshiharu Yamaguchi

Affiliation: The Cancer Institute Hospital of Japanese Foundation For Cancer Research (JFCR)

Project / Group Name: -

Funds / Grants (Research Project Number):

NameTitleProject Number
Project for Development of Innovative Research on Cancer Therapeutics (P-DIRECT), Japan Agency for Medical Research and Development (AMED) Development of the Intractable Cancer Therapies through the New Target Identification by the Molecular Profiling JP15cm0106060
JSPS KAKENHI

 

PUBLICATIONS

TitleDOIDataset ID
1 -
2

 

USRES (Controlled-access Data)

Principal Investigator: Affiliation: Data in Use (Dataset ID)Period of Data Use