NBDC Research ID: hum0369.v1

 

SUMMARY

Aims: There have been cases of what appear to be nosocomial infections among healthcare workers at several hospitals. The infected healthcare workers were assumed to have contracted the disease through close contact with infected patients. However, we confirmed at each hospital that there were many healthcare workers who had apparently had closer contact with infected patients than the infected healthcare workers but had not contracted the disease. The purpose of this study was to clarify the internal factors that make individuals less susceptible to novel coronavirus infection and their stress tolerance and to establish a system that contributes to the appropriate allocation of healthcare workers and the creation of a system that can more safely deal with this disease in the future.

Methods: Amplicon sequencing was performed using genomic DNA purified from peripheral blood.

Participants/Materials: 139 healthy individuals who had contacted patients infected with novel coronavirus but did not contract novel coronavirus

URL: https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000047878

 

Dataset IDType of DataCriteriaRelease Date
JGAS000562 NGS (Target Capture) Controlled-access (Type I) 2022/09/28

*Release Note

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JGAS000562

Participants/Materials 139 healthy individuals
Targets Target Capture
Target Loci for Capture Methods TMPRSS2, MxA, ACE2, IFNL3, and IFNL4
Platform Illumina [NextSeq 500]
Library Source DNAs extracted from peripheral blood cells
Cell Lines -
Library Construction (kit name) PCR amplicon sequencing (QIAseq Targeted DNA Custom Panel)
Fragmentation Methods Enzymatic fragmentation
Spot Type Paired-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers) 150 bp
Japanese Genotype-phenotype Archive Dataset ID JGAD000684
Total Data Volume 7.8 GB (fastq)
Comments (Policies) NBDC policy

 

DATA PROVIDER

Principal Investigator: Atsushi Kawaguchi

Affiliation: Division of Molecular Virology, Faculty of Medicine, University of Tsukuba

Project / Group Name: -

Funds / Grants (Research Project Number):

NameTitleProject Number
Health, Labour and Welfare Sciences Research Grants for Special Research Study to establish protective measures for health care workers treating COVID-19 infections 20CA2055

 

PUBLICATIONS

TitleDOIDataset ID
1
2

 

USRES (Controlled-access Data)

Principal InvestigatorAffiliationCountry/RegionResearch TitleData in Use (Dataset ID)Period of Data Use