NBDC Research ID: hum0133.v1

 

SUMMARY

Aims: Identification of molecular targets for development effective therapeutic methods and genomic or epigenomic markers for stratification of gastric cancer patients.

Methods: Exome analysis by using of Illumina HiSeq 2000

Participants/Materials: 214 normal, primary tumor, and metastasis tumor samples from 75 gastric cancer patients

 

Dataset IDType of DataCriteriaRelease Date
JGAS000086
NGS (Exome) Controlled-access (Type I) 2018/04/06

*Release Note

*Data users need to apply an application for Using NBDC Human Data to reach the Controlled-access Data. Learn more

 

MOLECULAR DATA

JGAS000086

Participants/Materials

gastric cancer: 75 cases (Total: 214 samples)

   non-tumor tissue: 75 samples

   tumor tissue (metastasis/recurrence): 139 samples

Targets Exome
Target Loci for Capture Methods -
Platform Illumina [HiSeq 2000]
Library Source DNAs extracted from tumor and non-tumor tissues from 75 gastric cancer patients
Cell Lines -
Library Construction (kit name) SureSelect Human All Exon V4 + lincRNA, SureSelect Human All Exon V5 + lincRNA
Fragmentation Methods Ultrasonic fragmentation (Covaris E220)
Spot Type Paired-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers) 100 bp
Japanese Genotype-phenotype Archive Dataset ID JGAD000086
Total Data Volume 5 TB (fastq [428 files])
Comments (Policies) NBDC policy

 

DATA PROVIDER

Principal Investigator: Toshiharu Yamaguchi

Affiliation: The Cancer Institute Hospital of Japanese Foundation For Cancer Research (JFCR)

Project / Group Name: -

Funds / Grants (Research Project Number):

NameTitleProject Number
Project for Development of Innovative Research on Cancer Therapeutics (P-DIRECT), Japan Agency for Medical Research and Development (AMED) Development of the Intractable Cancer Therapies through the New Target Identification by the Molecular Profiling JP15cm0106060
JSPS KAKENHI

 

PUBLICATIONS

TitleDOIDataset ID
1 -
2

 

USRES (Controlled-access Data)

Principal InvestigatorAffiliationResearch TitleData in Use (Dataset ID)Period of Data Use
Kouya Shiraishi Division of Genome Biology, National Cancer Research Institute Elucidation of immune-system networks between host and tumor based on genomic analysis JGAD000086 2019/08/05-2023/03/31
Masaki Mandai Kyoto University Faculty of Medicene, department of Gynecology and Obstetrics Integrated analyses of omics (genomics, transcriptomics, proteomics and metabolomics) associated with clinical variables for developing indivisualizedtreatment in gynecological malignancy JGAD000086 2020/03/13-2025/03/31