NBDC Research ID: hum0131.v1

 

SUMMARY

Aims: Transcriptome analysis for Williams Syndrome (WS)

Methods: RNA-sequencing

Participants/Materials: WS patients and healthy adult individuals

 

Dataset IDType of DataCriteriaRelease Date
JGAS000132 NGS (RNA-seq) Controlled-access (Type I) 2018/11/20

*Release Note

*Data users need to apply an application for Using NBDC Human Data to reach the Controlled-access Data. Learn more

 

MOLECULAR DATA

JGAS000132

Participants/Materials

6 WS patients (ICD10: Q253)

8 healthy adults as controls

Targets RNA-seq
Target Loci for Capture Methods -
Platform Thermo Fisher Scientific [Ion Proton]
Library Source RNAs extracted from peripheral blood cells
Cell Lines -
Library Construction (kit name) Ion Total RNA-Seq Kit v2
Fragmentation Methods Low input RiboMinus Eukaryote System v2
Spot Type Single-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers) 100 bp
Japanese Genotype-phenotype Archive Dataset ID JGAD000143
Total Data Volume 54 GB (fastq, txt [Transcripts Per Kilo-base Million: TPM])
Comments (Policies) NBDC policy & Company User Limit

 

DATA PROVIDER

Principal Investigator: Ryo Kimura

Affiliation: Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University

Project / Group Name: -

Funds / Grants (Research Project Number):

NameTitleProject Number
Core Research and Evolutional Science and Technology, Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED-CREST) Drug discovery for autism spectrum disorder based on epigenetic research JP16gm0510008
KAKENHI Grant-in-Aid for Scientific Research (C) Integrative network analysis of Williams syndrome 16K09965

 

PUBLICATIONS

TitleDOIDataset ID
1 Integrative network analysis reveals biological pathways associated with Williams syndrome doi: 10.1111/jcpp.12999 JGAD000143
2

 

USRES (Controlled-access Data)

Principal InvestigatorAffiliationCountry/RegionResearch TitleData in Use (Dataset ID)Period of Data Use
Michiaki Hamada Faculty of Science and Engineering, Waseda University Japan Construction of RNA-targeted Drug Discovery Database JGAD000143 2022/12/26-2025/03/31