NBDC Research ID: hum0059.v1

 

SUMMARY

Aims: Establishment of novel therapeutic strategy to overcome intractable cancer by molecular profiling of serous ovarian cancer

Methods: Exome analysis by using Illumina HiSeq 2000

Participants/Materials: 148 normal, primary tumor and relapse tumor tissues from 65 ovarian cancer

 

Dataset IDType of DataCriteriaRelease Date
JGAS000104 NGS (Exome) Controlled-access (Type I) 2018/04/06

*Release Note

*Data users need to apply an application for Using NBDC Human Data to reach the Controlled-access Data. Learn more

 

MOLECULAR DATA

JGAS000104

Participants/Materials

ovarian cancer: 65 cases (total: 148 samples)

   non-tumor tissues: 67 samples

   tumor tissues: 81 samples

Targets Exome
Target Loci for Capture Methods -
Platform Illumina [Hiseq 2000]
Library Source DNAs extracted from non-tumor, primary tumor, and relapse tumor tissues
Cell Lines -
Library Construction (kit name)

SureSelect Human All Exon V4 + lincRNA

SureSelect Human All Exon V5 + lincRNA

Fragmentation Methods Ultrasonic fragmentation (Covaris E220)
Spot Type Paired-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers) 100 bp
Japanese Genotype-phenotype Archive Dataset ID JGAD000109
Total Data Volume 3 TB (fastq)
Comments (Policies) NBDC policy

 

DATA PROVIDER

Principal Investigator: Kazuyoshi Kato

Affiliation: The Cancer Institute Hospital of JFCR

Project / Group Name: -

Funds / Grants (Research Project Number):

NameTitleProject Number
Project for Development of Innovative Research on Cancer Therapeutics (P-DIRECT), Japan Agency for Medical Research and Development (AMED) Development of the Intractable Cancer Therapies through the New Target Identification by the Molecular Profiling JP15cm0106061
JSPS KAKENHI

 

PUBLICATIONS

TitleDOIDataset ID
1 -

 

USRES (Controlled-access Data)

Principal InvestigatorAffiliationCountry/RegionResearch TitleData in Use (Dataset ID)Period of Data Use
Masaki Mandai Kyoto University Faculty of Medicene, department of Gynecology and Obstetrics Integrated analyses of omics (genomics, transcriptomics, proteomics and metabolomics) associated with clinical variables for developing indivisualizedtreatment in gynecological malignancy JGAD000109 2018/10/04-2025/03/31
Kouya Shiraishi Division of Genome Biology, National Cancer Research Institute Elucidation of immune-system networks between host and tumor based on genomic analysis JGAD000109 2019/08/05-2023/03/31
Noriomi Matsumura Department of Obstetrics and Gynecology, Faculty of Medicine, Kindai University Japan Integrated multi-omics analysis for ovarian clear cell adenocarcinoma: JGOG3017-TR1 JGAD000109 2024/10/15-2025/12/31
Ken Yamaguchi Gynecology and Obstetrics, Graduate School of Medicine and Faculty of Medicine, Kyoto University Japan Integrated multi-omics analysis for ovarian clear cell adenocarcinoma: JGOG3017-TR1 JGAD000109 2024/10/22-2025/12/31