RNA/Protein expression matrices and e/pQTL summary statistics from Wang, Q.S et al 2024.
(Statistically and functionally fine-mapped blood e/pQTLs from 1,405 humans reveal their distinct regulation patterns and disease relevance)

`protein_npx_matrix_wang_qs_et_al_2024_japan_covid19_taskforce.tsv.gz` are the plasma protein expression matrix, as measured in Olink Explore 3072 platform.

`rna_count_matrix_wang_qs_et_al_2024_japan_covid19_taskforce.tsv.gz` are the RNA expression (count) matrix, as measured in whole-blood RNA-seq

`rna_tpm_matrix_wang_qs_et_al_2024_japan_covid19_taskforce.tsv.gz` are the RNA expression (TPM) matrix, as measured in whole-blood RNA-seq

`eqtl_sumstats_wang_qs_et_al_2024_japan_covid19_taskforce.tsv.gz` are the summary statistics of cis-eQTL analysis.
Column descriptions:


`pqtl_sumstats_wang_qs_et_al_2024_japan_covid19_taskforce.tsv.gz` are the summary statistics of cis-pQTL analysis.
Column descriptions:


variant_id_hg19: chr:pos:ref:alt in hg19
variant_id_hg38: chr:pos:ref:alt in hg38
rsid: rsid based on dbSNP release 155, hg38
gene_id: Ensembl Gene ID
gene_name: Canonical gene name
tss_distance: Distance from the variant to the transcription starting site (TSS)
ma_samples: Number of samples with minor allele in the study sample (Japan COVID-19 Task Force, n=465)
ma_count: Number of minor alleles
maf: Minor allele frequency
pval_nominal: Nominal eQTL p-value calculated from fastQTL
slope: Effect size of the alternative allele
slope_se: Effect size standard error
pip_fm: Posterior inclusion probability (PIP) from FINEMAP
pip_susie: PIP from SuSiE
ref_is_minor: True if the reference allele is the minor allele in the study sample


Other notes:
- For expression matrices, sample IDs are anonymized, but the correpondance between RNA and protein expression matrices are retained.
- Only the variant-gene pairs with p<0.05 or PIP>0.001 are included in the cis-e/pQTL files
- The cis-e/pQTL data are sorted by variant_id_hg38 and tss_distance, ascending order.
(They do not necessarily correspond to genomic position order: e.g. chr10 comes earlier than chr2, based on alphabetical order)
- PIPs are set to 0 when lower than 0.001