# MS GWAS sumstats

## Files
Japanese meta: `MS_GWAS_sumstats.Japanese_meta.hg19.tsv.gz`  
European meta: `MS_GWAS_sumstats.European_meta.hg19.tsv.gz`  
African meta: `MS_GWAS_sumstats.African_meta.hg19.tsv.gz`  
Cross-population meta: `MS_GWAS_sumstats.CrossPop_meta.hg19.tsv.gz`  


## Columns
`CHR`: Chromosome  
`POS`: Position (hg19)  
`SNP`: SNP ID  
`EA`: Effect allele (alternative allele)  
`NEA`: Non-effect allele (reference allele)  
`P`: P-value  
`BETA`: Beta (log odds ratio)  
`SE`: Standard error  
`OR`: Odds ratio  
`Z`: Z-value  
`Direction`: Effect direction per study (order of studies are described below)  

Japanese meta only:  
`EAF`: Effect allele frequency  
`EAF_case`: Effect allele frequency in cases  
`EAF_ctrl`: Effect allele frequency in controls  

### Order of studies in Direction column
JPT_meta: Japanese Dataset 1, Japanese Dataset 2  
European meta: IMSGC+Andlauer, Genomics England, UKB, All of Us (EUR), MVP (EUR), FinnGen  
African meta: All of Us (AFR), MVP (AFR)  
Cross-population meta: Japanese Dataset 1, Japanese Dataset 2, IMSGC+Andlauer, Genomics England, UKB, All of Us (EUR), MVP (EUR), FinnGen, All of Us (AFR), MVP (AFR), All of Us (AMR)