These files were the results of GWAS of survival time in the Biobank Japan project released via National Bioscience Database Center (NBDC).
| File name | Number of samples | Number of variants |
|---|---|---|
| 2023_BBJ_SurvivalGWAS_male.txt.gz | 78,029* | 6,108,833 |
| 2023_BBJ_SurvivalGWAS_female.txt.gz | 59,664 | 6,108,833 |
*In the X chromosomal analysis, three individuals were excluded due to possible sex-errors.
| Number of column | column | description |
|---|---|---|
| 1 | SNP | marker name |
| 2 | CHR | chromosome |
| 3 | POS | position (hg19) |
| 4 | Ref | reference allele |
| 5 | Alt | alternative allele |
| 6 | Frq | alternative allele frequency |
| 7 | HR | hazard ratio (effect size of Alt) |
| 8 | CI95_L | lower 95% confidence interval |
| 9 | CI95_U | upper 95% confidence interval |
| 10 | P_cox | p-value estimated by wald test |
| 11 | p_spacox | p-value estimated by SPACox software. |
Association analysis was performed using 'survival' R package and SPACox software
(Bi W, et al. Am. J. Hum. Genet. 107, 222–233 [2020]).
The biobank Japan project National Bioscience Database Center Human Database RIKEN Center for Integrative Medical Sciences
If you use these date, please cite the following paper: Akiyama M et al. "Genome-wide association study reveals BET1L associated with survival time in the 137,693 Japanese individuals." Commun. Biol. (2023). DOI: XXXX