{"id":"hum0485","version":1,"url":"https://humandbs.dbcls.jp/research/hum0485/v1","datePublished":"2025-04-28","versions":[{"version":1,"datePublished":"2025-04-28"}],"title":{"ja":"シークエンス解析によるがんゲノム研究","en":"Genome sequencing analysis"},"summary":{"aims":{"ja":"胃がんの化学療法反応性を予測するための免疫およびゲノム解析","en":"Immunological and genomic analyses to predict chemotherapy response in gastric cancer"},"methods":{"ja":"shallow whole-genome sequencing（sWGS）、RNA sequencing","en":"shallow whole-genome sequencing (sWGS), RNA sequencing (RNA-seq)"},"targets":{"ja":"日本人胃がん65症例の腫瘍組織および非腫瘍組織","en":"Tumor and non-tumor tissues of 65 Japanese gastric cancer patients"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"配列決定","en":"Sequencing"},"targets":{"ja":"胃癌：65症例\n（日本人）","en":"65 gastric cancers\n(Japanese)"},"typeOfData":{"ja":"NGS\n（WGS、RNA-seq）","en":"NGS\n(WGS, RNA-seq)"}},"releaseNote":{"ja":"胃がん65症例の腫瘍組織および非腫瘍組織から抽出したDNAを用いたshallow whole-genome sequencing解析データ、ならびに、腫瘍組織から抽出したRNAを用いたRNA sequencing解析データをfastqファイルにて提供する。","en":"DNAs/RNAs extracted from tumor and non-tumor tissues obtained from gastric cancer patients were used for the shallow whole-genome sequencing and RNA sequencing analyses. Fastq files are provided."},"dataProviders":[{"name":{"ja":"中川 英刀","en":"Hidewaki Nakagawa"},"organization":{"name":{"ja":"理化学研究所 生命医科学研究センター がんゲノム研究チーム","en":"Laboratory of Genome Sequencing Analysis, RIKEN Center for Integrative Medical Sciences"}}}],"researchProjects":[],"grants":[{"title":{"ja":"がんゲノム解析による新規免疫療法および複合免疫療法開発のためのシーズ探索","en":"Search for seeds for the development of novel immunotherapies and combined immunotherapies by cancer genome analysis"},"agency":{"ja":"日本医療研究開発機構（AMED） 次世代がん医療創生研究事業（P-CREATE）","en":"Project for Cancer Research and Therapeutic Evolution (P-CREATE), Japan Agency for Medical Research and Development (AMED)"},"grantIds":["JP20cm0106552"]}],"relatedPublications":[{"title":"Predicting chemotherapy responsiveness in gastric cancer through machine learning analysis of genome, immune, and neutrophil signatures","doi":"https://doi.org/10.1007/s10120-024-01569-4","datasets":["JGAD000895"]}],"datasets":["JGAD000895"],"controlledAccessUsers":[]}