{"id":"hum0399","version":1,"url":"https://humandbs.dbcls.jp/research/hum0399/v1","datePublished":"2024-06-12","versions":[{"version":1,"datePublished":"2024-06-12"}],"title":{"ja":"乳がん微小環境形成に関わる分子生物学的機序の生体試料を用いた探索研究","en":"Exploratory studies of molecular biological mechanisms related to the breast cancer microenvironment"},"summary":{"aims":{"ja":"乳がんのリンパ節転移が免疫細胞に与える影響を遺伝子発現レベルで明らかにする","en":"To understand how metastasized breast cancer cells affect immune cells in lymph nodes"},"methods":{"ja":"10x Visiumによる空間トランスクリプトーム解析","en":"10x Visium-based spatial transcriptome analyses"},"targets":{"ja":"転移リンパ節を有する乳がん2症例の非転移リンパ節と転移リンパ節（計4検体）","en":"Two breast cancer patients harboring metastatic lymph nodes"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"発現\n病理画像","en":"Expression profiling, Histological imaging"},"targets":{"ja":"乳癌：2症例\n（日本人）","en":"breast cancer: 2 cases\n(Japanese)"},"typeOfData":{"ja":"NGS\n（Visium Spatial Gene Expression）\n病理画像","en":"NGS\n(Visium Spatial Gene Expression)\nHistological image"}},"releaseNote":{"ja":"転移リンパ節を有する乳がん2症例の非転移リンパ節ならびに転移リンパ節に対して実施したVisium空間トランスクリプトーム解析データを提供する（fastq、png、json、csv、tiff、tsv、mtx、cloupe、htmlファイル）。","en":"Non-metastatic and metastatic lymph node from breast cancer patients harboring metastatic lymph nodes were used for Visium Spatial Gene Expression Assay. Fastq, png, json, csv, tiff, tsv, mtx, cloupe, html files are provided."},"dataProviders":[{"name":{"ja":"河岡 慎平","en":"Shinpei Kawaoka"},"organization":{"name":{"ja":"京都大学 医生物学研究所","en":"Institute for Life and Medical Sciences, Kyoto University"}}}],"researchProjects":[],"grants":[{"title":{"ja":"先進ゲノム解析研究推進プラットフォーム","en":"Platform for Advanced Genome Sciences"},"agency":{"ja":"科学研究費助成事業 新学術領域研究","en":"KAKENHI Grant-in-Aid for Scientific Research on Innovative Areas"},"grantIds":["16H06279"]}],"relatedPublications":[],"datasets":["JGAD000745"],"controlledAccessUsers":[]}