{"id":"hum0306","version":1,"url":"https://humandbs.dbcls.jp/research/hum0306/v1","datePublished":"2021-10-15","versions":[{"version":1,"datePublished":"2021-10-15"}],"title":{"ja":"国際連携によるがんゲノムシークエンス解析（シークエンス解析によるがんゲノム研究）","en":"Cancer Genome Sequencing Analysis"},"summary":{"aims":{"ja":"がん患者から採取した腫瘍や組織の網羅的ゲノム解析を行い、そのデータを国際連携（ICGC）の場にて解析し、がんゲノムカタログを作成する。","en":"Cancer genome sequencing and analysis in international cancer genome collaboration ICGC for establishment of cancer genome catalogue"},"methods":{"ja":"長鎖一分子シークエンサー（nanopore）による全ゲノムシークエンス","en":"Whole genome sequencing with Nanopore sequencer"},"targets":{"ja":"国際がんゲノムコンソーシアム（ICGC）の際に収集した日本人肝臓がん9症例（hum0158においてshort read sequencerを用いた解析を実施している肝臓がん症例）の腫瘍組織由来DNA","en":"DNA extracted from tumor tissues of 9 liver cancer patients (also analyzed in hum0158 with short-read sequencer)"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"配列決定","en":"Sequencing"},"targets":{"ja":"肝臓癌：9症例\n（日本人）","en":"9 liver cancers\n(Japanese)"},"typeOfData":{"ja":"NGS\n（WGS）","en":"NGS\n(WGS)"}},"releaseNote":{"ja":"肝臓がん9症例の腫瘍組織から抽出したDNAを用いたロングリードWGS解析データをfastqファイルにて提供する。","en":"DNAs extracted from tumor tissues obtained from liver cancer patients were used for the long-read whole-genome sequencing analysis. Fastq files are provided."},"dataProviders":[{"name":{"ja":"中川 英刀","en":"Hidewaki Nakagawa"},"organization":{"name":{"ja":"理化学研究所 生命医科学研究センター がん免疫基盤研究部門 がんゲノム研究チーム","en":"Laboratory of Genome Sequencing Analysis, RIKEN Center for Integrative Medical Sciences"}}}],"researchProjects":[],"grants":[{"title":{"ja":"肝胆膵がんの多元的オミックス解析による分子機構の解明","en":"Multi-omics analysis for hepato-biliary-pancreatic cancers"},"agency":{"ja":"科学研究費助成事業 基盤研究（A）","en":"KAKENHI Grant-in-Aid for Scientific Research (A)"},"grantIds":["18H04049"]}],"relatedPublications":[{"title":"Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture","doi":"https://doi.org/10.1038/s41467-021-26805-8","datasets":["JGAD000475"]}],"datasets":["JGAD000475"],"controlledAccessUsers":[]}