{"id":"hum0290","version":1,"url":"https://humandbs.dbcls.jp/research/hum0290/v1","datePublished":"2022-03-07","versions":[{"version":1,"datePublished":"2022-03-07"},{"version":2,"datePublished":"2025-06-06"}],"title":{"ja":"ヒトゲノム・遺伝子発現および細菌叢の環境因子との相互作用に関する網羅的解析（2）","en":"Comprehensive analysis of interaction between human gene expression and environmental metagenomes."},"summary":{"aims":{"ja":"柏の葉地域に在勤・在住の健常者を対象としたゲノムコホート研究を通じ、より安心で快適な生活環境の実現、創薬研究・個別化医療の発展に向けた基盤構築","en":"Through genome cohort studies targeting healthy volunteers who work or live in the Kashiwa-no-ha area, we aim to realize a safer and more comfortable living environment and build a foundation for drug discovery research and the development of personalized medicine."},"methods":{"ja":"血液試料を用いたwhole genome aequencing解析、scRNA-seq解析、TCR-seq解析、BCR-seq解析、CyTOF解析、scATAC-seq解析、Olink解析、メチル化解析","en":"WGS, 10x scRNA, 10x TCR, 10x BCR, CyTOF, scATAC-seq, Olink, and methylation array analyses were performed using blood samples collected from healthy volunteers aged 18 years or older who worked or lived in the Kashiwa-no-ha area."},"targets":{"ja":"柏の葉地域に在勤・在住の18歳以上の健常者","en":"7 healthy volunteers aged 18 years or older who worked or lived in the Kashiwa-no-ha area"},"url":{"ja":[{"url":"https://kero.hgc.jp/longread_viewer/single_cell/open/","text":"https://kero.hgc.jp/longread_viewer/single_cell/open/"},{"url":"https://kero.hgc.jp/longread_viewer/single_cell/open/data/Expression/","text":"https://kero.hgc.jp/longread_viewer/single_cell/open/data/Expression/"}],"en":[{"url":"https://kero.hgc.jp/longread_viewer/single_cell/open/","text":"https://kero.hgc.jp/longread_viewer/single_cell/open/"},{"url":"https://kero.hgc.jp/longread_viewer/single_cell/open/data/Expression/","text":"https://kero.hgc.jp/longread_viewer/single_cell/open/data/Expression/"}]}},"listingSummary":{},"releaseNote":{"ja":"柏の葉地域に在勤・在住の18歳以上の健常者より採取した血液試料を用いた、WGS、10x scRNA、10x TCR、10x BCR、CyTOF解析の結果をfastqおよびtxtファイル形式で提供する。","en":"WGS, 10x scRNA, 10x TCR, 10x BCR, CyTOF analyses were performed using blood samples collected from healthy volunteers aged 18 years or older who worked or lived in the Kashiwa-no-ha area. Fastq and txt files are provided."},"dataProviders":[{"name":{"ja":"鈴木 穣","en":"Yutaka Suzuki"},"organization":{"name":{"ja":"東京大学大学院 新領域創成科学研究科 メディカル情報生命専攻 生命システム観測分野","en":"Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo"}}}],"researchProjects":[],"grants":[{"title":{"ja":"ウイルス-人体相互作用ネットワークの理解と制御","en":"Understanding and Control of Virus-Human Interaction Networks"},"agency":{"ja":"JST Moonshot R&D - MILLENNIA Program","en":"JST Moonshot R&D - MILLENNIA Program"},"grantIds":["JPMJMS2025"]}],"relatedPublications":[{"title":"Intensive Single Cell Analysis Reveals Immune Cell Diversity among Healthy Individuals","doi":"https://doi.org/10.26508/lsa.202201398","datasets":["JGAD000432"]},{"title":"Multimodal single-cell analyses of peripheral blood mononuclear cells of COVID-19 patients in Japan","doi":"https://doi.org/10.1038/s41598-023-28696-9","datasets":["JGAD000432"]}],"datasets":["JGAD000432"],"controlledAccessUsers":[]}