{"id":"hum0262","version":1,"url":"https://humandbs.dbcls.jp/research/hum0262/v1","datePublished":"2021-05-11","versions":[{"version":1,"datePublished":"2021-05-11"}],"title":{"ja":"非小細胞肺癌における微小管阻害薬および葉酸代謝阻害薬感受性のバイオマーカー研究","en":"Identification of biomarkers for prediction of efficacy of microtubule inhibitors and antifolates in non-small cell lung cancer"},"summary":{"aims":{"ja":"発現モジュール解析に基づいた肺腺癌における微小管阻害剤効果予測マーカーの探索","en":"Identification of predictive markers based on transcriptome modules for microtubule inhibitors of lung adenocarcinoma patients"},"methods":{"ja":"RNAシークエンス","en":"RNA sequencing"},"targets":{"ja":"肺腺がん24症例","en":"Lung Adenocarcinoma, 24 cases"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"発現","en":"Expression profiling"},"targets":{"ja":"肺腺癌：24症例\n（日本人）","en":"Lung Adenocarcinoma: 24 cases\n(Japanese)"},"typeOfData":{"ja":"NGS\n（RNA-seq）","en":"NGS\n(RNA-seq)"}},"releaseNote":{"ja":"肺腺がん24症例の腫瘍組織から抽出したRNAを用いたRNA-seqデータをfastqファイルにて提供する。","en":"RNAs extracted from tumor tissues of 24 patients with lung adenocarcinoma were used for the RNA-sequencing analysis. Fastq files are provided."},"dataProviders":[{"name":{"ja":"土原 一哉","en":"Katsuya Tsuchihara"},"organization":{"name":{"ja":"国立がん研究センター 先端医療開発センター トランスレーショナルインフォマティクス分野","en":"Division of Tranaslational Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center"}}}],"researchProjects":[],"grants":[{"title":{"ja":"進行肺がん大規模クリニカルシークエンスデータを用いた個別化治療法の開発","en":"Precision medicine of advanced lung cancer based on Pan-Japan clinical sequencing data"},"agency":{"ja":"日本医療研究開発機構（AMED） 革新的がん医療実用化研究事業","en":"Practical Research for Innovative Cancer Control, Japan Agency for Medical Research and Development (AMED)"},"grantIds":["JP19ck0106255"]},{"title":{"ja":"次世代トランスクリプトーム解析技術の開発と応用","en":"Development of the next generation transcriptome analysis and its application"},"agency":{"ja":"科学研究費助成事業 新学術領域研究（研究領域提案型）","en":"KAKENHI Grant-in-Aid for Scientific Research on Priority Areas (Research in a proposed research area)"},"grantIds":["17H06306"]}],"relatedPublications":[],"datasets":["JGAD000370"],"controlledAccessUsers":[{"principalInvestigator":{"ja":"浜田 道昭","en":"Michiaki Hamada"},"affiliation":{"ja":"浜田研究室, 理工学術院, 早稲田大学","en":"Hamada Laboratory, Faculty of Science and Engineering, Waseda University"},"country":{"ja":"日本","en":"Japan"},"researchTitle":{"ja":"RNA標的創薬データベースの構築","en":"Construction of RNA-targeted Drug Discovery Database"},"periodStart":"2023-01-05","periodEnd":"2027-10-31","datasets":["JGAD000370"]}]}