{"id":"hum0245","version":1,"url":"https://humandbs.dbcls.jp/research/hum0245/v1","datePublished":"2022-10-25","versions":[{"version":1,"datePublished":"2022-10-25"}],"title":{"ja":"思春期・若年成人急性リンパ芽球性白血病における網羅的ゲノム解析（JALSG ALL202U-GWS）","en":"Comprehensive Genome analysis of adult acute lymphoblastic leukemia (JALSG ALL202U-GWS)"},"summary":{"aims":{"ja":"急性リンパ性白血病（Acute Lymphoblastic Leukemia: ALL）のゲノム解析による分子病態の解明","en":"Elucidation of molecular pathology for acute lymphocytic leukemia (ALL) by genomic analysis"},"methods":{"ja":"Target Capture Sequencing解析","en":"Target Capture Sequencing Analysis"},"targets":{"ja":"フィラデルフィア染色体陰性ALL","en":"Philadelphia chromosome-negative (Ph-negative) ALL"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"配列決定","en":"Sequencing"},"targets":{"ja":"フィラデルフィア染色体陰性ALL：46症例\n（日本人）","en":"46 patients with Ph-negative ALL\n(Japanese)"},"typeOfData":{"ja":"NGS\n（Target Capture）","en":"NGS\n(Target Capture)"}},"releaseNote":{"ja":"フィラデルフィア染色体陰性急性リンパ性白血病46症例の白血病細胞から抽出したDNAを対象とした110遺伝子のTarget Capture Sequencing解析データをbamファイルにて提供する。","en":"DNA extracted from leukemia cells of 46 patients with Philadelphia chromosome-negative acute lymphoblastic leukemia were used for target capture sequencing analysis. Bam files are provided."},"dataProviders":[{"name":{"ja":"早川 文彦","en":"Fumihiko Hayakawa"},"organization":{"name":{"ja":"名古屋大学大学院 医学系研究科 病態解析学講座","en":"Pathophysiological Laboratory Sciences, Nagoya University School of Medicine"}}}],"researchProjects":[{"name":{"ja":"JALSG ALL202-U","en":"JALSG ALL202-U"},"url":{"ja":null,"en":null}}],"grants":[{"title":{"ja":"AYA世代急性リンパ性白血病の小児型治療法および遺伝子パネル診断による層別化治療に関する研究","en":"Treatment with a pediatric protocols and stritified strateiesy by gene panel testing for adolescents and young adults with acute lymphoblastic leukemia"},"agency":{"ja":"日本医療研究開発機構（AMED） 革新的がん医療実用化研究事業","en":"Practical Research for Innovative Cancer Control, Japan Agency for Medical Research and Development (AMED)"},"grantIds":["JP19ck0106331"]}],"relatedPublications":[{"title":"Two novel high-risk adult B-cell acute lymphoblastic leukemia subtypes with high expression of CDX2 and IDH1/2 mutations","doi":"https://doi.org/10.1182/blood.2021011921","datasets":["JGAD000382"]}],"datasets":["JGAD000382"],"controlledAccessUsers":[]}