{"id":"hum0239","version":1,"url":"https://humandbs.dbcls.jp/research/hum0239/v1","datePublished":"2020-07-27","versions":[{"version":1,"datePublished":"2020-07-27"}],"title":{"ja":"がん、感染症、難病、生活習慣病等に関する遺伝子とタンパク質などの網羅的解析","en":"Genomic and Proteomic comprehensive analysis related to cancer, infectious diseases, intractable diseases and lifestyle-related diseases"},"summary":{"aims":{"ja":"膀胱がん患者におけるがん組織のゲノムプロファイルの解明","en":"To reveal the genome profiles in urothelial bladder cancer"},"methods":{"ja":"multiplex PCRで増幅した対象領域を次世代シークエンス技術により解読し、がん組織で生じている体細胞変異を解明する","en":"Amplicon Target Sequencing Analysis"},"targets":{"ja":"膀胱がん患者の腫瘍組織","en":"Patients with urothelial bladder cancer"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"配列決定","en":"Sequencing"},"targets":{"ja":"膀胱癌：19症例\n（日本人）","en":"19 patients with urothelial bladder cancer\n(Japanese)"},"typeOfData":{"ja":"NGS\n（Target Capture）","en":"NGS\n(Target Capture)"}},"releaseNote":{"ja":"膀胱がん19症例の腫瘍組織から抽出したDNAを用いたTarget Capture Sequencing解析結果をbamファイルにて提供する。","en":"DNAs extracted from tumor tissues of 19 patients with urothelial bladder cancer were used for a target capture sequencing analysis. Bam files are provided."},"dataProviders":[{"name":{"ja":"弘津 陽介","en":"Yosuke Hirotsu"},"organization":{"name":{"ja":"山梨県立中央病院 ゲノム解析センター","en":"Genome Analysis Center, Yamanashi Central Hospital"}}}],"researchProjects":[],"grants":[],"relatedPublications":[{"title":"Genomic Profiling Identified ERCC2 E606Q Mutation in Helicase Domain Respond to Platinum-Based Neoadjuvant Therapy in Urothelial Bladder Cancer","doi":"https://doi.org/10.3389/fonc.2020.01643","datasets":["JGAD000341"]}],"datasets":["JGAD000341"],"controlledAccessUsers":[]}