{"id":"hum0238","version":1,"url":"https://humandbs.dbcls.jp/research/hum0238/v1","datePublished":"2020-07-28","versions":[{"version":1,"datePublished":"2020-07-28"}],"title":{"ja":"オーダーメイド医療開発プロジェクト","en":"Development of personalized medicine"},"summary":{"aims":{"ja":"ヒトDNA塩基配列に確認された内在性ヒトヘルペスウイルス6（HHV-6）配列の同定","en":"To determine human herpesvirus 6 (HHV-6) sequences in human genome sequences"},"methods":{"ja":"全ゲノムシーケンスデータの内、ヒト参照配列にマップしなかったリード配列より再構築を行った","en":"Reconstruction of integrated HHV-6 sequences from whole genome sequencing data of BioBank Japan (BBJ) participants using unmapped reads"},"targets":{"ja":"HHV-6のゲノム挿入が確認された検体","en":"BBJ participants whose DNA sequences contain germline integration of HHV-6 sequences"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"配列決定","en":"Sequencing"},"targets":{"ja":"BBJ：10名\n（日本人）","en":"3 participants of BBJ\n(Japanese)"},"typeOfData":{"ja":"NGS\n（WGS）","en":"NGS\n(WGS)"}},"releaseNote":{"ja":"オーダーメイド医療の実現プログラムにおいて実施した全ゲノムシーケンスデータの内、HHV-6のゲノム挿入が確認された10サンプルにおいて、ヒト参照配列にマップしなかったリードから再構築したHHV-6のゲノム挿入配列をchromosome_fastaファイルにて提供する。","en":"Integrated HHV-6 sequences were reconstructed from whole-genome sequening data of 10 BioBank Japan participants using unmapped reads. Chromosome_fasta files are provided."},"dataProviders":[{"name":{"ja":"桃沢 幸秀","en":"Yukihide Momozawa"},"organization":{"name":{"ja":"理化学研究所 生命医科学研究センター 基盤技術開発研究チーム","en":"Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences"}}},{"name":{"ja":"Nicholas Parrish","en":"Nicholas Parrish"},"organization":{"name":{"ja":"理化学研究所 生命医科学研究センター ゲノム免疫生物学理研白眉研究チーム","en":"Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Center for Integrative Medical Sciences"}}}],"researchProjects":[],"grants":[],"relatedPublications":[{"title":"Endogenization and excision of human herpesvirus 6 in human genomes","doi":"https://doi.org/10.1101/2019.12.19.882522","datasets":["JGAD000340"]}],"datasets":["JGAD000340"],"controlledAccessUsers":[]}