{"id":"hum0237","version":1,"url":"https://humandbs.dbcls.jp/research/hum0237/v1","datePublished":"2021-03-05","versions":[{"version":1,"datePublished":"2021-03-05"}],"title":{"ja":"日本人の全ゲノム、RNA解析を基盤とした老年病関連分子の同定と解析","en":"Whole genome and RNA analysis of geriatric disease in Japanese"},"summary":{"aims":{"ja":"アルツハイマー病の関連遺伝子群を同定し予知診断、治療に応用する","en":"Application to future medicine by analyzing Alzheimer's disease associated genes"},"methods":{"ja":"ジェノタイピングアレイデータを用いたアルツハイマー病のゲノムワイド関連解析（GWAS）","en":"Genome wide association study"},"targets":{"ja":"アルツハイマー病3,962症例、非アルツハイマー病4,074名","en":"Alzheimer's disease"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"ゲノムワイド関連","en":"Genome-wide association"},"targets":{"ja":"アルツハイマー病：3,962症例\n非アルツハイマー病：4,074名\n（日本人）","en":"Alzheimer's disease: 3,962 cases\n4,074 controls\n(Japanese)"},"typeOfData":{"ja":"SNP-chip","en":"SNP-chip"}},"releaseNote":{"ja":"アルツハイマー病3962症例、非アルツハイマー病4074名の末梢血から抽出したDNAを用いて遺伝子型を決定し、GWASを実施した結果（統計情報）をテキストファイルにて提供する。","en":"DNAs extracted from peripheral blood cells of 3,962 patiants with Alzheimer's disease and 4,074 controls were genotyped and a genome-wide association study was performed. Statistical analyses data is provided as txt files."},"dataProviders":[{"name":{"ja":"尾崎 浩一","en":"Kouichi Ozaki"},"organization":{"name":{"ja":"国立長寿医療研究センター メディカルゲノムセンター 臨床ゲノム解析推進部","en":"Division for Genomic medicine, Medical Genome Center, National Center for Geriatrics and Gerontology"}}}],"researchProjects":[],"grants":[{"title":{"ja":"認知症臨床ゲノム情報データベース構築に関する開発研究","en":"Genome wide association study and data storage of dementia in a large Japanese population"},"agency":{"ja":"日本医療研究開発機構（AMED） 臨床ゲノム情報統合データベース整備事業","en":"Program for Integrated Database of Clinical and Genomic Information, Japan Agency for Medical Research and Development (AMED)"},"grantIds":["JP18kk0205009"]}],"relatedPublications":[{"title":"Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Alzheimer's disease risk in Japanese","doi":"https://doi.org/10.1038/s41398-021-01272-3","datasets":["NHA000161"]}],"datasets":["NHA000161"],"controlledAccessUsers":[]}