{"id":"hum0231","version":1,"url":"https://humandbs.dbcls.jp/research/hum0231/v1","datePublished":"2024-07-22","versions":[{"version":1,"datePublished":"2024-07-22"}],"title":{"ja":"ヒト疾患特異的iPS細胞樹立に関する研究","en":"A study for the establishment of disease-specific iPS cells."},"summary":{"aims":{"ja":"iPS細胞を用いた疾患研究の対照とするため、健常人からiPS細胞を樹立する。試料提供者（ドナー）のゲノムを解析し、疾患関連変異の有無を確認する。","en":"To serve as control cases, iPS cells are established from healthy donors. The genome of donors will be examined."},"methods":{"ja":"ドナーから末梢血単核球を採取し、Whole Exome Seqencing解析を実施する","en":"Whole Exome Sequencing analysis was performed with blood cells of donors."},"targets":{"ja":"健診受診者","en":"Healthy volunteers"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"配列決定","en":"Sequencing"},"targets":{"ja":"健常人：120名\n（日本人）","en":"120 Healthy volunteers\n(Japanese)"},"typeOfData":{"ja":"NGS\n（Exome）","en":"NGS\n(Exome)"}},"releaseNote":{"ja":"健常人120名の末梢血単核球から抽出したDNAを用いたWhole Exome Sequencingデータの解析結果をfastqファイルにて提供する。","en":"DNAs extracted from PBMCs of 120 healthy volunteers were used for the whole exome sequencing analysis. Fastq files are provided."},"dataProviders":[{"name":{"ja":"齋藤 潤","en":"Megumu K. Saito"},"organization":{"name":{"ja":"京都大学iPS細胞研究所","en":"Center for iPS cell resarch and application, Kyoto University"}}}],"researchProjects":[],"grants":[{"title":{"ja":"疾患特異的iPS細胞樹立促進のための基盤形成","en":"Fundamental research of promote establishment of disease-specific iPS cells"},"agency":{"ja":"日本医療研究開発機構（AMED） 疾患特異的iPS細胞の利活用促進・難病研究加速プログラム","en":"The Program for Intractable Diseases Research utilizing Disease-specific iPS cells, Japan Agency for Medical Research and Development (AMED)"},"grantIds":["JP16bm0609001"]},{"title":{"ja":"日本人健常人集団由来iPS細胞株の構築","en":"Construction of comprehensive iPSC library on Japanese healthy donors"},"agency":{"ja":"日本医療研究開発機構（AMED） 疾患特異的iPS細胞の利活用促進・難病研究加速プログラム","en":"The Program for Intractable Diseases Research utilizing Disease-specific iPS cells, Japan Agency for Medical Research and Development (AMED)"},"grantIds":["JP19bm0804001"]},{"title":{"ja":null,"en":null},"agency":{"ja":"京都大学iPS細胞研究所 iPS細胞研究基金","en":"iPS cell research fund, Center for iPS cell research and application, Kyoto university"},"grantIds":null}],"relatedPublications":[],"datasets":["JGAD000393"],"controlledAccessUsers":[]}