{"id":"hum0223","version":1,"url":"https://humandbs.dbcls.jp/research/hum0223/v1","datePublished":"2020-09-01","versions":[{"version":1,"datePublished":"2020-09-01"}],"title":{"ja":"血液がんにおける遺伝子変異の解析","en":"The analyses of gene mutations in hematology malignancy"},"summary":{"aims":{"ja":"血液がん患者の初発時及び再発時の検体を用いて特定の遺伝子の変異解析を行い、病状進行度のサロゲートマーカーになるかどうかを検討する。","en":"To clarify of the disease status of myeloma and lymphoma by somatic gene mutation analyses"},"methods":{"ja":"初発時および再発時における骨髄検査検体の骨髄腫細胞より抽出したDNAを用いた126遺伝子のTarget Capture Sequencing解析","en":"gene mutaion analyses using NGS technology at the point of diagnosis, relapse, or proceeding disease"},"targets":{"ja":"多発性骨髄腫","en":"multiple myeloma"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"配列決定","en":"Sequencing"},"targets":{"ja":"多発性骨髄腫：7症例\n（日本人）","en":"7 patients with multiple myeloma\n(Japanese)"},"typeOfData":{"ja":"NGS\n（Target Capture）","en":"NGS\n(Target Capture)"}},"releaseNote":{"ja":"多発性骨髄腫7症例の初発時および再発時の骨髄穿刺吸引検体（骨髄腫細胞）より抽出したDNAを用いたTarget Capture Sequencing解析結果をvcfファイルにて提供する。","en":"DNAs extracted from myeloma cells isolated from bone marrow samples of 7 patients with multiple myeloma (samples collected at the point of diagnosis and relapse or proceeding disease) were used for a target capture sequencing analysis. Vcf files are provided."},"dataProviders":[{"name":{"ja":"照井 康仁","en":"Yasuhito Terui"},"organization":{"name":{"ja":"がん研有明病院 血液腫瘍科","en":"Dept of Hematology Oncology, The Cancer Institute Hospital of JFCR"}}}],"researchProjects":[],"grants":[],"relatedPublications":[{"title":"The clonal evolution during long-term clinical course of multiple myeloma","doi":"https://doi.org/10.1007/s12185-020-02979-7","datasets":["JGAD000326"]}],"datasets":["JGAD000326"],"controlledAccessUsers":[]}