{"id":"hum0128","version":1,"url":"https://humandbs.dbcls.jp/research/hum0128/v1","datePublished":"2018-10-29","versions":[{"version":1,"datePublished":"2018-10-29"}],"title":{"ja":"慢性好酸球性炎症疾患の網羅的遺伝子解析と網羅的蛋白質解析に関する研究","en":"A study on comprehensive genome and proteome analyses of the chronic eosinophillic inflammatory diseases."},"summary":{"aims":{"ja":"好酸球性副鼻腔炎の病態解析","en":"To investigate the pathology of eosinophilic chronic rhinosinusitis"},"methods":{"ja":"慢性副鼻腔炎症例の鼻茸から抽出したRNAを用いたRNA-seq","en":"RNAs were extracted from nasal polyps of 6 patients with chronic rhinosinusitis, and performed RNA sequencing."},"targets":{"ja":"好酸球性副鼻腔炎を含む慢性副鼻腔炎症例","en":"Patients with chronic rhinosinusitis with nasal polyp"},"url":{"ja":null,"en":null}},"listingSummary":{"methods":{"ja":"発現","en":"Expression profiling"},"targets":{"ja":"慢性副鼻腔炎：6症例\n（日本人）","en":"6 chronic rhinosinusitis with nasal polyps\n(Japanese)"},"typeOfData":{"ja":"NGS\n（RNA-seq）","en":"NGS\n(RNA-seq)"}},"releaseNote":{"ja":"好酸球性副鼻腔炎を含む慢性副鼻腔炎6症例の鼻茸から抽出したRNAを用いたRNA-seqのリードカウントデータをテキストファイルにて提供する。TruSeq RNA Sample Prep KitによるRNAライブラリ作製後、Illumina [HiSeq 2000]にて平均長100 bpを読んだ（Paired-end）。","en":"RNAs were extracted from nasal polyps of 6 chronic rhinosinusitis patients. Libraries for RNA-seq were prepared with TruSeq RNA Sample Prep Kit and RNA-seq was performed with Illumina [HiSeq 2000] (100 bp, Paired-end). Read count data from RNA-seq are provided as txt files."},"dataProviders":[{"name":{"ja":"藤枝 重治","en":"Shigeharu Fujieda"},"organization":{"name":{"ja":"福井大学医学部 耳鼻咽喉科・頭頸部外科学","en":"Departments of Otorhinolaryngology Head & Neck Surgery, Faculty of Medical Sciences, University of Fukui"}}}],"researchProjects":[],"grants":[{"title":{"ja":"重症好酸球性副鼻腔炎に対する新しい治療戦略","en":"Novel strategy of the treatment for severe eosinophilic chronic rhinosinusitis."},"agency":{"ja":"日本医療研究開発機構（AMED） 難治性疾患実用化研究事業","en":"Practical Research Project for Rare / Intractable Diseases, Japan Agency for Medical Research and Development (AMED)"},"grantIds":["JP16ek0109062"]}],"relatedPublications":[{"title":"Periostin as a novel biomarker for postoperative recurrence of chronic rhinosinitis with nasal polyps","doi":"https://doi.org/10.1038/s41598-018-29612-2","datasets":["JGAD000231"]}],"datasets":["JGAD000231"],"controlledAccessUsers":[{"principalInvestigator":{"ja":"浜田 道昭","en":"Michiaki Hamada"},"affiliation":{"ja":"浜田研究室, 理工学術院, 早稲田大学","en":"Hamada Laboratory, Faculty of Science and Engineering, Waseda University"},"country":{"ja":"日本","en":"Japan"},"researchTitle":{"ja":"RNA標的創薬データベースの構築","en":"Construction of RNA-targeted Drug Discovery Database"},"periodStart":"2023-01-05","periodEnd":"2027-10-31","datasets":["JGAD000231"]}]}