{"id":"hum0013","version":1,"url":"https://humandbs.dbcls.jp/research/hum0013/v1","datePublished":"2014-10-16","versions":[{"version":1,"datePublished":"2014-10-16"}],"title":{"ja":"日本PGxデータサイエンスコンソーシアム PGx研究のための日本人健常者2994名のSNP遺伝子型データ","en":"Japan PGx Data Science Consortium Database"},"summary":{"aims":{"ja":"安全性・有効性の高い薬剤開発を目的とした日本人のコントロールDNAデータベースの構築","en":"To build a Japanese control DNA database for application to genetic investigations on adverse drug reactions and facilitate in the development of drugs with high efficacy and safety."},"methods":{"ja":"illumina HumanOmni2.5-8 BeadChipを使用し、約240万個の一塩基多型（Single Nucleotide Variants：SNVs）の遺伝子型を決定する","en":"Determine the genotype of nearly 2.5 million single nucleotide polymorphisms (SNPs) by using of illumina HumanOmni2.5-8."},"targets":{"ja":"日本人健常人2994名","en":"2994 Japanese healthy controls"},"url":{"ja":[{"url":"https://humandbs.dbcls.jp/hum0013-jpdsc","text":"JPDSC"}],"en":[{"url":"https://humandbs.dbcls.jp/en/hum0013-jpdsc","text":"JPDSC"}]}},"listingSummary":{"methods":{"ja":"ゲノムワイド\n健常者内頻度","en":"Genome-wide allele frequency in control set"},"targets":{"ja":"健常者：2994名\n（日本人）","en":"2994 Participants\n(Japanese)"},"typeOfData":{"ja":"SNP-chip","en":"SNP-chip"}},"releaseNote":{"ja":"このバージョンでは、日本人健常人集団2994例の遺伝子データベースを構築する上で使用したマーカーの頻度情報。遺伝子型決定には、Illumina [HumanOmni2.5-8 BeadChip]を使用している。","en":"Determine the genotype of nearly 2.5 million single nucleotide polymorphisms (SNPs) by using of illumina HumanOmni2.5-8 BeadChip."},"dataProviders":[{"name":{"ja":"末松 浩嗣","en":"Koji Suematsu"},"organization":{"name":{"ja":"大正製薬株式会社","en":"PGx, Clinical Research, Taisho Pharmaceutical Co., Ltd."}}}],"researchProjects":[{"name":{"ja":"日本ファーマコジェノミクスデータサイエンスコンソーアム（JPDSC）","en":"The Japan PGx Data Science Consortium (JPDSC)"},"url":{"ja":[{"url":"https://www.jstage.jst.go.jp/article/faruawpsj/46/5/46_KJ00009581938/_pdf/-char/ja","text":"https://www.jstage.jst.go.jp/article/faruawpsj/46/5/46_KJ00009581938/_pdf/-char/ja"}],"en":[{"url":"https://doi.org/10.1038/jhg.2015.23","text":"https://doi.org/10.1038/jhg.2015.23"}]}}],"grants":[],"relatedPublications":[{"title":"Specific HLA types are associated with antiepileptic drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese subjects.","doi":"https://doi.org/10.2217/pgs.13.180","datasets":["NHA000003"]},{"title":"A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients.","doi":"https://doi.org/10.1038/tpj.2011.41","datasets":["NHA000003"]}],"datasets":["NHA000003"],"controlledAccessUsers":[]}