{"id":"hum0012","version":1,"url":"https://humandbs.dbcls.jp/research/hum0012/v1","datePublished":"2015-08-19","versions":[{"version":1,"datePublished":"2015-08-19"}],"title":{"ja":"ながはま0次コホート事業","en":"Nagahama Zero-ji Preventive Cohort Project"},"summary":{"aims":{"ja":"市民の健康づくりの推進と予防医学の発展への貢献","en":"Contribution to the promotion of the citizen's health and the development of the preventive medicine"},"methods":{"ja":"アレイによる遺伝子型データ（一般市民を対象とする多目的コホート研究）","en":"Genotypes were determined by using of several SNP-arrays (Multipurpose prospective cohort study about the citizen)"},"targets":{"ja":"3712名","en":"3712 Japanese participants"},"url":{"ja":[{"url":"https://zeroji-cohort.com/project/index.html","text":"https://zeroji-cohort.com/project/index.html"}],"en":[{"url":"https://zeroji-cohort.com/english/","text":"https://zeroji-cohort.com/english/"}]}},"listingSummary":{"methods":{"ja":"ゲノムワイド関連\n健常者遺伝子型","en":"Genome-wide association, control set cohort genotyping"},"targets":{"ja":"健常者：3712名\n（日本人）","en":"3712 Participants\n(Japanese)"},"typeOfData":{"ja":"SNP-chip","en":"SNP-chip"}},"releaseNote":{"ja":"滋賀県長浜市民3712名の遺伝子について、6種のIllumina Genotypine Arrays [Human610-Quad, HumanOmni2.5-4v1, HumanOmni2.5-8v1, HumanOmni2.5S-8v1, HumanExome-12v, HumanCoreExome-12v1] を使用し決定した遺伝子型情報です。\n検体-プラットフォーム対応表はこちら。","en":"Genotypes for 3712 participants living in Nagahama city were determined using Illumina SNP arrays [Human610-Quad, HumanOmni2.5-4v1, HumanOmni2.5-8v1, HumanOmni2.5S-8v1, HumanExome-12v1, HumanCoreExome-12v1].\nThe sample-platform correspondence table is here."},"dataProviders":[{"name":{"ja":"松田 文彦","en":"Fumihiko Matsuda"},"organization":{"name":{"ja":"京都大学医学研究科附属ゲノム医学センター","en":"Center for Genomic Medicine Kyoto University Graduate School of Medicine"}}}],"researchProjects":[{"name":{"ja":"ながはま0次コホート事業","en":"Nagahama Zero-ji preventive cohort project"},"url":{"ja":[{"url":"https://zeroji-cohort.com/project/index.html","text":"https://zeroji-cohort.com/project/index.html"}],"en":[{"url":"https://zeroji-cohort.com/english/","text":"https://zeroji-cohort.com/english/"}]}}],"grants":[{"title":{"ja":"網羅的統合オミックス解析を用いた難病の原因究明と 新規診断・治療法の確立","en":"Investigating the cause for intractable diseases using comprehensive integrated omics analyses and the establishment of new diagnostics / treatment"},"agency":{"ja":"厚生労働科学研究費補助金 難病・がん等の疾患分野の医療の実用化研究事業","en":"Health and Labor Sciences Research Grants - Research Project on Applying Health Technology"},"grantIds":["11103334"]},{"title":{"ja":"ゲノム医学を用いた地域疫学コホート事業 ー大学と自治体の連携による21世紀型の新たな健康づくりの試みー","en":"Regional cohort project using genomic medicine"},"agency":{"ja":"特別研究経費（運営費交付金）","en":"Special Research Grant (Management Expenses Grants)"},"grantIds":null},{"title":{"ja":"1万人ゲノム疫学コホートを用いた生活習慣病の遺伝因子の解明","en":"Elucidation of genetic factors responsible for lifestyle diseases using the 10,000 genome cohort"},"agency":{"ja":"武田科学振興財団 特定研究助成金","en":"Takeda Science Foundation (The Specific Research Grant)"},"grantIds":null}],"relatedPublications":[{"title":"A genome-wide association study of serum levels of prostate specific antigen in the Japanese population.","doi":"https://doi.org/10.1136/jmedgenet-2014-102423","datasets":["JGAD000012"]},{"title":"Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels","doi":"https://doi.org/10.1038/ncomms8754","datasets":["JGAD000012"]}],"datasets":["JGAD000012"],"controlledAccessUsers":[{"principalInvestigator":{"ja":"野口 恵美子","en":"Emiko Noguchi"},"affiliation":{"ja":"医学医療系遺伝医学, 筑波大学","en":"Department of Medical Genetics, Faculty of Medicine, University of Tsukuba"},"country":{"ja":"日本","en":"Japan"},"researchTitle":{"ja":"グルパール19S（旧茶のしずく抗原）によるアレルギー反応に関連する遺伝子マーカーの探索(H25-088)","en":"Identification of genes related to allergy against hydrozyed wheat protein."},"periodStart":"2016-08-25","periodEnd":"2022-03-07","datasets":["JGAD000012"]},{"principalInvestigator":{"ja":"岡田 随象","en":"Yukinori Okada"},"affiliation":{"ja":"遺伝統計学, 大阪大学大学院医学系研究科","en":"Department of Statistical Genetics, Osaka University Graduate School of Medicine"},"country":{"ja":"日本","en":"Japan"},"researchTitle":{"ja":"日本人由来B細胞株DNAのゲノムデータを用いた遺伝統計解析手法の研究","en":"Development of statistical genetic analysis methods using the whole-genome data from B cell lines of Japanese\nindividuals"},"periodStart":"2019-10-17","periodEnd":"2029-03-31","datasets":["JGAD000012"]},{"principalInvestigator":{"ja":"朝野 仁裕","en":"Yoshihiro Asano"},"affiliation":{"ja":"大学院医学系研究科循環器内科学, 大阪大学","en":"Department of Cardiovascular Medicine Graduate School of Medicine, Osaka University"},"country":{"ja":"日本","en":"Japan"},"researchTitle":{"ja":"遺伝性心血管疾患の感受性遺伝子解析研究","en":"Sensitive gene analysis of hereditary cardiovascular disease"},"periodStart":"2021-06-24","periodEnd":"2027-05-31","datasets":["JGAD000012"]},{"principalInvestigator":{"en":"Gregor Kuhlenbaeumer"},"affiliation":{"en":"Neurogenetics within Dept. of Neurology, UKSH"},"country":{"ja":"ドイツ","en":"Germany"},"researchTitle":{"en":"Conducting a genome-wide association study investigating antibody-mediated encephalitides. "},"periodStart":"2022-04-07","periodEnd":"2026-12-31","datasets":["JGAD000012"]},{"principalInvestigator":{"ja":"吉田 善紀","en":"Yoshinori Yoshida"},"affiliation":{"ja":"増殖分化機構研究部門, 京都大学iPS細胞研究所","en":"Yoshida Lab  Cell growth and differentiation, Kyoto University, Center for iPS Cell Research and Application"},"country":{"ja":"日本","en":"Japan"},"researchTitle":{"ja":"肥大型心筋症の診療実態に関する多施前向き登録研究","en":"Prospective REgistry to eVAluate the predIctors and clinicaL management of HCM"},"periodStart":"2022-12-27","periodEnd":"2030-03-31","datasets":["JGAD000012"]}]}