{"id":"JGAD000931","research":"hum0030","url":"https://humandbs.dbcls.jp/dataset/JGAD000931","datePublished":"2025-07-09","dateModified":"2025-07-09","values":[{"key":"access-criteria","label":{"ja":"アクセス制限","en":"Access criteria"},"type":"vocabulary","terms":[{"code":"controlled-access-type-1","label":{"ja":"制限公開（Type I）","en":"Controlled-access (Type I)"}}]},{"key":"type-of-data","label":{"ja":"データの種類","en":"Type of data"},"type":"text","text":{"ja":"NGS（Exome）","en":"NGS (Exome)"}}],"experiments":[{"label":"WES","values":[{"key":"materials-and-participants","label":{"ja":"材料と対象者","en":"Materials and participants"},"type":"text","text":{"ja":"卵巣がん（ICD10：C56, D391）：189症例（腫瘍組織190検体、非腫瘍組織189検体）\n卵巣がんの内訳は以下の通りです。\n卵巣高異型度漿液性がん：161症例（腫瘍組織162検体、非腫瘍組織161検体）\n卵巣類内膜がん：5症例（腫瘍組織5検体、非腫瘍組織5検体）\n卵巣がん肉腫：2症例（腫瘍組織2検体、非腫瘍組織2検体）\n卵巣脱分化がん：2症例（腫瘍組織2検体、非腫瘍組織2検体）\n卵巣明細胞がん：10症例（腫瘍組織10検体、非腫瘍組織10検体）\n転移性卵巣悪性腫瘍：4症例（腫瘍組織4検体、非腫瘍組織4検体）\n卵巣境界悪性腫瘍：2症例（腫瘍組織2検体、非腫瘍組織2検体）\n卵巣粘液性がん/境界悪性腫瘍：3症例（腫瘍組織3検体、非腫瘍組織3検体）\n卵巣低異型度漿液性がん：1症例（腫瘍組織1検体、非腫瘍組織1検体）","en":"Ovarian cancer (ICD10: C56, D391): 189 cases (tumor tissue: 190, non-tumor tissue: 189)\nOvarian High-Grade Serous Carcinoma: 161 cases (tumor tissue: 162, non-tumor tissue 161)\nOvarian Endometrioid Carcinoma: 5 cases (tumor tissue: 5, non-tumor tissue 5)\nOvarian Carcinosarcoma: 2 cases (tumor tissue: 2, non-tumor tissue 2)\nOvarian De-differentiated Carcinoma: 2 cases (tumor tissue: 2, non-tumor tissue 2)\nOvarian Clear Cell Carcinoma: 10 cases (tumor tissue: 10, non-tumor tissue 10)\nOvarian Metastatic Tumors: 4 cases (tumor tissue: 4, non-tumor tissue 4)\nOvarian Borderline Tumors: 2 cases (tumor tissue: 2, non-tumor tissue 2)\nOvarian Mucinous Carcinoma/Borderline: 3 cases (tumor tissue: 3, non-tumor tissue 3)\nOvarian Low-Grade Serous Carcinoma: 1 case (tumor tissue: 1, non-tumor tissue 1)"}},{"key":"disease","label":{"ja":"疾患","en":"Disease"},"type":"disease","diseases":[{"terms":[{"code":"C56","label":{"ja":"卵巣の悪性新生物＜腫瘍＞","en":"Malignant neoplasm of ovary"}},{"code":"D391","label":{"ja":"卵巣","en":"Neoplasm of uncertain or unknown behaviour: Ovary"}}],"name":{"ja":"卵巣がん","en":"Ovarian cancer"}}]},{"key":"health-status","label":{"ja":"健康状態","en":"Health status"},"type":"vocabulary","terms":[{"code":"affected","label":{"ja":"罹患","en":"Affected"}}]},{"key":"subject-count","label":{"ja":"対象者数","en":"Subject count"},"type":"number","numbers":[{"value":189,"unit":null,"high":null}]},{"key":"subject-count-type","label":{"ja":"対象者数の数え方","en":"Counted as"},"type":"vocabulary","terms":[{"code":"individual","label":{"ja":"人数","en":"Individual"}}]},{"key":"sample-description","label":{"ja":"試料説明","en":"Sample description"},"type":"text","text":{"ja":"腫瘍組織および非腫瘍組織（末梢血）から抽出したDNA","en":"DNAs extracted from tumor tissues and non-tumor tissues (peripheral blood cells)"}},{"key":"tissue","label":{"ja":"組織","en":"Tissue"},"type":"vocabulary","terms":[{"code":"peripheral-blood","label":{"ja":"末梢血","en":"Peripheral blood"}}]},{"key":"is-tumor","label":{"ja":"腫瘍 / 非腫瘍","en":"Tumor / normal"},"type":"vocabulary","terms":[{"code":"mixed","label":{"ja":"混在","en":"Mixed"}}]},{"key":"sample-provider","label":{"ja":"試料の入手元","en":"Sample provider"},"type":"text","text":{"ja":null,"en":null}},{"key":"experimental-method","label":{"ja":"実験方法","en":"Experimental method"},"type":"vocabulary","terms":[{"code":"wes","label":{"en":"WES"}}]},{"key":"targets","label":{"ja":"測定対象","en":"Target"},"type":"text","text":{"ja":null,"en":null}},{"key":"fragmentation","label":{"ja":"断片化","en":"Fragmentation"},"type":"text","text":{"ja":null,"en":null}},{"key":"platform","label":{"ja":"プラットフォーム","en":"Platform"},"type":"vocabulary","terms":[{"code":"illumina-nextseq-500","label":{"en":"Illumina NextSeq 500"}}]},{"key":"read-type","label":{"ja":"リードタイプ","en":"Read type"},"type":"vocabulary","terms":[{"code":"paired-end","label":{"ja":"ペアエンド","en":"Paired-end"}}]},{"key":"read-length","label":{"ja":"リード長","en":"Read length"},"type":"number","numbers":[{"value":150,"unit":"bp","high":null}]},{"key":"reference-sequence","label":{"ja":"参照ゲノム","en":"Reference genome"},"type":"vocabulary","terms":[{"code":"grch38","label":{"en":"GRCh38"}}]},{"key":"mapping","label":{"ja":"マッピング","en":"Mapping"},"type":"text","text":{"ja":"BWA、Novoalign","en":"BWA, Novoalign"}},{"key":"mapping-quality","label":{"ja":"マッピング品質","en":"Mapping quality"},"type":"text","text":{"ja":"MAPQ>20","en":"MAPQ>20"}},{"key":"coverage-depth","label":{"ja":"カバレッジ (深度)","en":"Coverage (depth)"},"type":"number","numbers":[{"value":152,"unit":"x","high":null,"prefix":{"ja":"腫瘍組織: ","en":"Tumor tissue: "}},{"value":81.5,"unit":"x","high":null,"prefix":{"ja":"非腫瘍組織: ","en":"Non-tumor tissue: "}}]},{"key":"policies","label":{"ja":"利用ポリシー","en":"Data use policy"},"type":"vocabulary","terms":[{"code":"nbdc-data-sharing-policy-jgap000001","label":{"ja":"NBDC データ共有ポリシー (JGAP000001)","en":"NBDC data sharing policy (JGAP000001)"}}]}]}],"dataVolume":6430713153657,"fileFormats":[{"code":"fastq","label":{"en":"FASTQ"}},{"code":"bam","label":{"en":"BAM"}},{"code":"bai","label":{"en":"BAI"}}]}