{"id":"JGAD000790","research":"hum0433","url":"https://humandbs.dbcls.jp/dataset/JGAD000790","datePublished":"2024-09-26","dateModified":"2025-08-26","values":[{"key":"access-criteria","label":{"ja":"アクセス制限","en":"Access criteria"},"type":"vocabulary","terms":[{"code":"controlled-access-type-1","label":{"ja":"制限公開（Type I）","en":"Controlled-access (Type I)"}}]},{"key":"type-of-data","label":{"ja":"データの種類","en":"Type of data"},"type":"text","text":{"ja":"NGS（RNA-seq）","en":"NGS (RNA-seq)"}}],"experiments":[{"label":"RNA-seq","values":[{"key":"materials-and-participants","label":{"ja":"材料と対象者","en":"Materials and participants"},"type":"text","text":{"ja":"妊娠高血圧症候群（ICD10：O149）：10症例26検体（分娩後の胎盤と脱落膜組織から樹立したヒト胎盤幹細胞株）\n3症例：各3検体（細胞性栄養膜細胞、絨毛外栄養膜細胞、合胞体栄養膜細胞）\n7症例：各1検体（合胞体栄養膜細胞）\n10症例：各1検体（低酸素曝露後のヒト胎盤幹細胞株）\n正常妊娠：11名28検体（分娩後の胎盤と脱落膜組織から樹立したヒト胎盤幹細胞株）\n3名：各3検体（細胞性栄養膜細胞、絨毛外栄養膜細胞、合胞体栄養膜細胞）\n8名：各1検体（合胞体栄養膜細胞）\n11症例：各1検体（低酸素曝露後のヒト胎盤幹細胞株）","en":"hypertensive disorders of pregnancy (ICD10: O149): 10 cases\ntrophoblast stem cells derived from placenta after delivery\n3 cases; 3 samples (hTSC, EVT, ST) each\n7 cases; 1 sample (ST) each\n10 cases; 1 sample (hypoxia-treated hTSCs) each\nnormal pregnancy: 11 subjects\ntrophoblast stem cells derived from placenta after delivery\n3 cases; 3 samples (hTSC, EVT, ST) each\n8 cases; 1 sample (ST) each\n11 cases; 1 sample (hypoxia-treated hTSCs) each"}},{"key":"disease","label":{"ja":"疾患","en":"Disease"},"type":"disease","diseases":[{"terms":[{"code":"O149","label":{"ja":"子かん＜癇＞前症，詳細不明","en":"Pre-eclampsia, unspecified"}}],"name":{"ja":"妊娠高血圧症候群","en":"hypertensive disorders of pregnancy"}}]},{"key":"health-status","label":{"ja":"健康状態","en":"Health status"},"type":"vocabulary","terms":[{"code":"mixed","label":{"ja":"混在","en":"Mixed"}}]},{"key":"subject-count","label":{"ja":"対象者数","en":"Subject count"},"type":"number","numbers":[{"value":21,"unit":null,"high":null}]},{"key":"subject-count-type","label":{"ja":"対象者数の数え方","en":"Counted as"},"type":"vocabulary","terms":[{"code":"individual","label":{"ja":"人数","en":"Individual"}}]},{"key":"sex","label":{"ja":"性別","en":"Sex"},"type":"vocabulary","terms":[{"code":"female","label":{"ja":"女性","en":"Female"}}]},{"key":"sample-description","label":{"ja":"試料説明","en":"Sample description"},"type":"text","text":{"ja":"ヒト胎盤幹細胞株および栄養膜細胞より抽出したRNA","en":"RNAs extracted from trophoblast stem cells and CT cells"}},{"key":"tissue","label":{"ja":"組織","en":"Tissue"},"type":"vocabulary","terms":[{"code":"placenta","label":{"ja":"胎盤","en":"Placenta"}},{"code":"trophoblast-stem-cell","label":{"ja":"栄養膜幹細胞","en":"Trophoblast stem cell"}},{"code":"decidua","label":{"ja":"脱落膜","en":"Decidua"}}]},{"key":"is-tumor","label":{"ja":"腫瘍 / 非腫瘍","en":"Tumor / normal"},"type":"vocabulary","terms":[{"code":"normal","label":{"ja":"非腫瘍","en":"Normal"}}]},{"key":"cell-line","label":{"ja":"細胞株","en":"Cell line"},"type":"vocabulary","terms":[{"code":"trophoblast-stem-cell-ts","label":{"en":"Trophoblast stem cell (TS)"}},{"code":"extravillous-trophoblast-evt","label":{"en":"Extravillous trophoblast (EVT)"}},{"code":"syncytiotrophoblast-st","label":{"en":"Syncytiotrophoblast (ST)"}}]},{"key":"sample-provider","label":{"ja":"試料の入手元","en":"Sample provider"},"type":"text","text":{"ja":null,"en":null}},{"key":"experimental-method","label":{"ja":"実験方法","en":"Experimental method"},"type":"vocabulary","terms":[{"code":"rna-seq","label":{"en":"RNA-seq"}}]},{"key":"targets","label":{"ja":"測定対象","en":"Target"},"type":"text","text":{"ja":null,"en":null}},{"key":"reagents","label":{"ja":"試薬キット","en":"Reagent kit"},"type":"vocabulary","terms":[{"code":"nebnext-ultra-ii-directional-rna-library-prep-kit-for-illumina","label":{"en":"NEBNext Ultra II Directional RNA Library Prep Kit for Illumina"}}]},{"key":"fragmentation","label":{"ja":"断片化","en":"Fragmentation"},"type":"text","text":{"ja":"上記キットに準拠","en":"included in the above library construction kit"}},{"key":"platform","label":{"ja":"プラットフォーム","en":"Platform"},"type":"vocabulary","terms":[{"code":"illumina-novaseq-6000","label":{"en":"Illumina NovaSeq 6000"}}]},{"key":"read-type","label":{"ja":"リードタイプ","en":"Read type"},"type":"vocabulary","terms":[{"code":"paired-end","label":{"ja":"ペアエンド","en":"Paired-end"}}]},{"key":"read-length","label":{"ja":"リード長","en":"Read length"},"type":"number","numbers":[{"value":150,"unit":"bp","high":null}]},{"key":"policies","label":{"ja":"利用ポリシー","en":"Data use policy"},"type":"vocabulary","terms":[{"code":"nbdc-data-sharing-policy-jgap000001","label":{"ja":"NBDC データ共有ポリシー (JGAP000001)","en":"NBDC data sharing policy (JGAP000001)"}}]}]}],"dataVolume":180079712119,"fileFormats":[{"code":"fastq","label":{"en":"FASTQ"}}]}