{"id":"JGAD000318","research":"hum0225","url":"https://humandbs.dbcls.jp/dataset/JGAD000318","datePublished":"2020-09-28","dateModified":"2020-11-18","values":[{"key":"access-criteria","label":{"ja":"アクセス制限","en":"Access criteria"},"type":"vocabulary","terms":[{"code":"controlled-access-type-1","label":{"ja":"制限公開（Type I）","en":"Controlled-access (Type I)"}}]},{"key":"type-of-data","label":{"ja":"データの種類","en":"Type of data"},"type":"text","text":{"ja":"NGS（Target Capture）","en":"NGS (Target Capture)"}}],"experiments":[{"label":"Targeted DNA sequencing","values":[{"key":"materials-and-participants","label":{"ja":"材料と対象者","en":"Materials and participants"},"type":"text","text":{"ja":"HAM（ICD-10：A858/B973）：21症例（46検体）\n感染細胞分画（腫瘍組織）：23検体（2症例は成人T細胞白血病[ATL]発症後の検体を含む）\n非感染細胞分画（非腫瘍組織）：23検体（2症例はATL発症後の検体を含む）","en":"HAM (ICD-10: A858/B973): 21 cases (46 samples)\ninfected cells (tumor cells): 23 samples (including post-ATL specimens for 2 cases)\nuninfected cells (non-tumor cells): 23 samples (including post-ATL specimens for 2 cases)"}},{"key":"disease","label":{"ja":"疾患","en":"Disease"},"type":"disease","diseases":[{"terms":[{"code":"A858","label":{"ja":"その他の明示されたウイルス（性）脳炎","en":"Other specified viral encephalitis"}},{"code":"B973","label":{"ja":"他章に分類される疾患の原因であるレトロウイルス","en":"Retrovirus as the cause of diseases classified to other chapters"}}],"name":{"ja":"HAM","en":"HAM"}}]},{"key":"health-status","label":{"ja":"健康状態","en":"Health status"},"type":"vocabulary","terms":[{"code":"affected","label":{"ja":"罹患","en":"Affected"}}]},{"key":"subject-count","label":{"ja":"対象者数","en":"Subject count"},"type":"number","numbers":[{"value":46,"unit":null,"high":null}]},{"key":"subject-count-type","label":{"ja":"対象者数の数え方","en":"Counted as"},"type":"vocabulary","terms":[{"code":"sample","label":{"ja":"検体数","en":"Sample"}}]},{"key":"sample-description","label":{"ja":"試料説明","en":"Sample description"},"type":"text","text":{"ja":"末梢血単核球（PBMC）の感染細胞分画（腫瘍組織）及び非感染細胞分画（非腫瘍組織）から抽出したDNA","en":"DNAs extracted from PBMC (infected and uninfected cells) of HAM patients"}},{"key":"tissue","label":{"ja":"組織","en":"Tissue"},"type":"vocabulary","terms":[{"code":"peripheral-blood","label":{"ja":"末梢血","en":"Peripheral blood"}},{"code":"pbmc","label":{"ja":"末梢血単核球 (PBMC)","en":"PBMC"}}]},{"key":"is-tumor","label":{"ja":"腫瘍 / 非腫瘍","en":"Tumor / normal"},"type":"vocabulary","terms":[{"code":"mixed","label":{"ja":"混在","en":"Mixed"}}]},{"key":"sample-provider","label":{"ja":"試料の入手元","en":"Sample provider"},"type":"text","text":{"ja":null,"en":null}},{"key":"experimental-method","label":{"ja":"実験方法","en":"Experimental method"},"type":"vocabulary","terms":[{"code":"targeted-dna-sequencing","label":{"en":"Targeted DNA sequencing"}}]},{"key":"targets","label":{"ja":"測定対象","en":"Target"},"type":"text","text":{"ja":"ATLリスク50遺伝子を含む280遺伝子とHTLV-1 provirus全長領域","en":"280 genes (human) including 50 candidate genes for ATL and whole genome of HTLV-1 provirus"}},{"key":"reagents","label":{"ja":"試薬キット","en":"Reagent kit"},"type":"vocabulary","terms":[{"code":"sureselect-xt-hs","label":{"en":"SureSelect XT HS"}}]},{"key":"fragmentation","label":{"ja":"断片化","en":"Fragmentation"},"type":"text","text":{"ja":"超音波断片化（Covaris）","en":"Ultrasonic fragmentation (Covaris)"}},{"key":"platform","label":{"ja":"プラットフォーム","en":"Platform"},"type":"vocabulary","terms":[{"code":"illumina-hiseq-2500","label":{"en":"Illumina HiSeq 2500"}},{"code":"illumina-hiseq-3000","label":{"en":"Illumina HiSeq 3000"}}]},{"key":"read-type","label":{"ja":"リードタイプ","en":"Read type"},"type":"vocabulary","terms":[{"code":"paired-end","label":{"ja":"ペアエンド","en":"Paired-end"}}]},{"key":"read-length","label":{"ja":"リード長","en":"Read length"},"type":"number","numbers":[{"value":100,"unit":"bp","high":null}]},{"key":"policies","label":{"ja":"利用ポリシー","en":"Data use policy"},"type":"vocabulary","terms":[{"code":"nbdc-data-sharing-policy-jgap000001","label":{"ja":"NBDC データ共有ポリシー (JGAP000001)","en":"NBDC data sharing policy (JGAP000001)"}}]}]}],"dataVolume":256454766976,"fileFormats":[{"code":"fastq","label":{"en":"FASTQ"}},{"code":"bed","label":{"en":"BED"}}]}