{"id":"JGAD000313","research":"hum0145","url":"https://humandbs.dbcls.jp/dataset/JGAD000313","datePublished":"2020-09-28","dateModified":"2020-11-18","values":[{"key":"access-criteria","label":{"ja":"アクセス制限","en":"Access criteria"},"type":"vocabulary","terms":[{"code":"controlled-access-type-1","label":{"ja":"制限公開（Type I）","en":"Controlled-access (Type I)"}}]},{"key":"type-of-data","label":{"ja":"データの種類","en":"Type of data"},"type":"text","text":{"ja":"NGS（Target Capture）","en":"NGS (Target Capture)"}}],"experiments":[{"label":"Targeted DNA sequencing","values":[{"key":"materials-and-participants","label":{"ja":"材料と対象者","en":"Materials and participants"},"type":"text","text":{"ja":"大腸がん（ICD10：C189）：10症例 36検体\n・術前化学療法前に内視鏡を用いて採取した原発巣の腫瘍組織：10症例 10検体\n・術前化学療法後切除切片の腫瘍組織：10症例 10検体\n・術前化学療法後切除切片の非腫瘍組織：10症例 10検体\n・末梢血の血漿：3症例 4検体\n・転移巣切除切片の腫瘍組織：2症例 2検体","en":"Colorectal cancer (ICD10: C189): 10 cases (36 samples)\n- Primary tumor tissues obtained by endoscopic biopsy prior to NAC: 10 cases (10 samples)\n- Tumor tissues from resected specimens after NAC: 10 cases (10 samples)\n- Non-tumor tissues from resected specimens after NAC: 10 cases (10 samples)\n- Blood plasma: 3 cases (4 samples)\n- Metastatic tumor tissues from resected specimens: 2 cases (2 samples)"}},{"key":"disease","label":{"ja":"疾患","en":"Disease"},"type":"disease","diseases":[{"terms":[{"code":"C189","label":{"ja":"結腸，部位不明","en":"Malignant neoplasm: Colon, unspecified"}}],"name":{"ja":"大腸がん","en":"Colorectal cancer"}}]},{"key":"health-status","label":{"ja":"健康状態","en":"Health status"},"type":"vocabulary","terms":[{"code":"mixed","label":{"ja":"混在","en":"Mixed"}}]},{"key":"subject-count","label":{"ja":"対象者数","en":"Subject count"},"type":"number","numbers":[{"value":36,"unit":null,"high":null}]},{"key":"subject-count-type","label":{"ja":"対象者数の数え方","en":"Counted as"},"type":"vocabulary","terms":[{"code":"sample","label":{"ja":"検体数","en":"Sample"}}]},{"key":"sample-description","label":{"ja":"試料説明","en":"Sample description"},"type":"text","text":{"ja":"大腸がんの原発巣（FFPE）、手術切除切片の腫瘍組織と非腫瘍組織、血漿、転移巣切除切片の腫瘍組織から抽出したから抽出したDNA","en":"DNAs extracted from tumor and matched non-tumor tissues from CRCs"}},{"key":"tissue","label":{"ja":"組織","en":"Tissue"},"type":"vocabulary","terms":[{"code":"plasma","label":{"ja":"血漿","en":"Plasma"}}]},{"key":"is-tumor","label":{"ja":"腫瘍 / 非腫瘍","en":"Tumor / normal"},"type":"vocabulary","terms":[{"code":"mixed","label":{"ja":"混在","en":"Mixed"}}]},{"key":"sample-provider","label":{"ja":"試料の入手元","en":"Sample provider"},"type":"text","text":{"ja":null,"en":null}},{"key":"experimental-method","label":{"ja":"実験方法","en":"Experimental method"},"type":"vocabulary","terms":[{"code":"targeted-dna-sequencing","label":{"en":"Targeted DNA sequencing"}}]},{"key":"targets","label":{"ja":"測定対象","en":"Target"},"type":"text","text":{"ja":"ClearSeq Halo HS Cancer Research Panel","en":"ClearSeq Halo HS Cancer Research Panel"}},{"key":"reagents","label":{"ja":"試薬キット","en":"Reagent kit"},"type":"vocabulary","terms":[{"code":"sureselect-target-enrichment-system","label":{"en":"SureSelect Target Enrichment System"}},{"code":"haloplex-target-enrichment","label":{"en":"HaloPlex Target Enrichment"}}]},{"key":"fragmentation","label":{"ja":"断片化","en":"Fragmentation"},"type":"text","text":{"ja":"酵素反応","en":"Enzymatic fragmentation"}},{"key":"platform","label":{"ja":"プラットフォーム","en":"Platform"},"type":"vocabulary","terms":[{"code":"illumina-hiseq-2500","label":{"en":"Illumina HiSeq 2500"}}]},{"key":"read-type","label":{"ja":"リードタイプ","en":"Read type"},"type":"vocabulary","terms":[{"code":"paired-end","label":{"ja":"ペアエンド","en":"Paired-end"}}]},{"key":"read-length","label":{"ja":"リード長","en":"Read length"},"type":"number","numbers":[{"value":100,"unit":"bp","high":null}]},{"key":"policies","label":{"ja":"利用ポリシー","en":"Data use policy"},"type":"vocabulary","terms":[{"code":"nbdc-data-sharing-policy-jgap000001","label":{"ja":"NBDC データ共有ポリシー (JGAP000001)","en":"NBDC data sharing policy (JGAP000001)"}}]}]}],"dataVolume":207937199120,"fileFormats":[{"code":"fastq","label":{"en":"FASTQ"}}]}