{"id":"JGAD000061","research":"hum0064","url":"https://humandbs.dbcls.jp/dataset/JGAD000061","datePublished":"2020-09-28","dateModified":"2020-11-18","values":[{"key":"access-criteria","label":{"ja":"アクセス制限","en":"Access criteria"},"type":"vocabulary","terms":[{"code":"controlled-access-type-1","label":{"ja":"制限公開（Type I）","en":"Controlled-access (Type I)"}}]},{"key":"type-of-data","label":{"ja":"データの種類","en":"Type of data"},"type":"text","text":{"ja":"【ゲノム・遺伝子解析研究】大腸がん、胃がん、肺がんの臨床情報、多型情報、発現情報、メチル化情報\n【後ろ向き研究】大腸がん、胃がん、肺がん、糖尿病・腎障害、循環器疾患、呼吸器疾患症例の臨床情報","en":"1. Genome & Genetic research\ngenotype, methylation, gene expression, clinical data for colorectal, gastric, or lung cancer patients.\n2. Retrospective study\nclinical data for colorectal cancer, gastric cancer, lung cancer, cardiovascular disorders, respiratory dysfunction, diabetes, or nephropathy patients."}}],"experiments":[{"label":"Sanger sequencing + TaqMan + qRT-PCR + Microarray (薬剤代謝遺伝子 SNP / がん)","values":[{"key":"materials-and-participants","label":{"ja":"材料と対象者","en":"Materials and participants"},"type":"text","text":{"ja":"大腸がん：106症例、胃がん：62症例、肺がん：173症例","en":"colorectal cancer: 106 cases\ngastric cancer: 62 cases\nlung cancer: 173 cases"}},{"key":"health-status","label":{"ja":"健康状態","en":"Health status"},"type":"vocabulary","terms":[{"code":"affected","label":{"ja":"罹患","en":"Affected"}}]},{"key":"subject-count","label":{"ja":"対象者数","en":"Subject count"},"type":"number","numbers":[{"value":341,"unit":null,"high":null}]},{"key":"subject-count-type","label":{"ja":"対象者数の数え方","en":"Counted as"},"type":"vocabulary","terms":[{"code":"individual","label":{"ja":"人数","en":"Individual"}}]},{"key":"age-group","label":{"ja":"年齢層","en":"Age group"},"type":"vocabulary","terms":[{"code":"mixed","label":{"ja":"混在","en":"Mixed"}}]},{"key":"sample-description","label":{"ja":"試料説明","en":"Sample description"},"type":"text","text":{"ja":"【ダイレクトシークエンス法】 腫瘍組織もしくは非腫瘍組織から抽出したDNA\n【TaqMan法】 腫瘍組織もしくは非腫瘍組織から抽出したDNA\n【qRT-PCR法】 腫瘍組織から抽出したRNA\n【COBRA法】 腫瘍組織から抽出したDNA\n【マイクロアレイ法】 腫瘍組織から抽出したRNA","en":"-Direct sequencing DNAs extracted from tumors or non-cancerous tissues\n-TaqMan analysis DNAs extracted from tumors or non-cancerous tissues\n-qRT-PCR RNAs extracted from tumors\n-COBRA assay DNAs extracted from tumors\n-cDNA microarray RNAs extracted from tumors"}},{"key":"is-tumor","label":{"ja":"腫瘍 / 非腫瘍","en":"Tumor / normal"},"type":"vocabulary","terms":[{"code":"mixed","label":{"ja":"混在","en":"Mixed"}}]},{"key":"experimental-method","label":{"ja":"実験方法","en":"Experimental method"},"type":"vocabulary","terms":[{"code":"sanger-sequencing","label":{"en":"Sanger sequencing"}},{"code":"qrt-pcr","label":{"en":"qRT-PCR"}},{"code":"expression-array","label":{"en":"Expression array"}}]},{"key":"targets","label":{"ja":"測定対象","en":"Target"},"type":"text","text":{"ja":null,"en":null}},{"key":"reagents","label":{"ja":"試薬キット","en":"Reagent kit"},"type":"vocabulary","terms":[{"code":"taqman-snp-genotyping-assays","label":{"en":"TaqMan SNP Genotyping Assays"}},{"code":"absolute-qpcr-mix","label":{"en":"ABsolute QPCR Mix"}},{"code":"ez-dna-methylation-gold-kit","label":{"en":"EZ DNA Methylation-Gold Kit"}},{"code":"amplitaq-gold","label":{"en":"AmpliTaq Gold"}},{"code":"quick-amp-labeling-kit","label":{"en":"Quick-Amp Labeling Kit"}}]},{"key":"platform","label":{"ja":"プラットフォーム","en":"Platform"},"type":"vocabulary","terms":[{"code":"applied-biosystems-genetic-analyzer-3130","label":{"en":"Applied Biosystems Genetic Analyzer 3130"}},{"code":"roche-lightcycler-480ii","label":{"en":"Roche LightCycler 480II"}},{"code":"agilent-whole-human-genome-microarray-4x44k","label":{"en":"Agilent Whole Human Genome Microarray 4x44K"}},{"code":"agilent-dna-microarray-scanner","label":{"en":"Agilent DNA Microarray Scanner"}}]},{"key":"normalization","label":{"ja":"正規化","en":"Normalization"},"type":"text","text":{"ja":"JGA000061の実験の補足情報を参照のこと","en":"Refer to JGA000061 experimental support information"}},{"key":"has-phenotype-data","label":{"ja":"表現型データの有無","en":"Phenotype data"},"type":"vocabulary","terms":[{"code":"included","label":{"ja":"あり","en":"Included"}}]},{"key":"policies","label":{"ja":"利用ポリシー","en":"Data use policy"},"type":"vocabulary","terms":[{"code":"nbdc-data-sharing-policy-jgap000001","label":{"ja":"NBDC データ共有ポリシー (JGAP000001)","en":"NBDC data sharing policy (JGAP000001)"}}]}]},{"label":"臨床・治療情報","values":[{"key":"materials-and-participants","label":{"ja":"材料と対象者","en":"Materials and participants"},"type":"text","text":{"ja":"【がん症例】\n大腸がん：313 症例\n胃がん：166 症例\n肺がん：344 症例\n\n【非がん症例】\n糖尿病・腎障害：300 症例\n循環器疾患：357 症例\n呼吸器疾患：49 症例","en":"2-1. Cancer cases\ncolorectal cancer: 313 cases\ngastric cancer: 166 cases\nlung cancer: 344 cases\n\n2-2. Non-cancerous cases\ndiabetes and nephropathy: 300 cases\ncardiovascular disorder: 357 cases\nrespiratory dysfunction: 49 cases"}},{"key":"health-status","label":{"ja":"健康状態","en":"Health status"},"type":"vocabulary","terms":[{"code":"mixed","label":{"ja":"混在","en":"Mixed"}}]},{"key":"subject-count","label":{"ja":"対象者数","en":"Subject count"},"type":"number","numbers":[{"value":1529,"unit":null,"high":null}]},{"key":"subject-count-type","label":{"ja":"対象者数の数え方","en":"Counted as"},"type":"vocabulary","terms":[{"code":"individual","label":{"ja":"人数","en":"Individual"}}]},{"key":"age-group","label":{"ja":"年齢層","en":"Age group"},"type":"vocabulary","terms":[{"code":"mixed","label":{"ja":"混在","en":"Mixed"}}]},{"key":"has-phenotype-data","label":{"ja":"表現型データの有無","en":"Phenotype data"},"type":"vocabulary","terms":[{"code":"included","label":{"ja":"あり","en":"Included"}}]},{"key":"policies","label":{"ja":"利用ポリシー","en":"Data use policy"},"type":"vocabulary","terms":[{"code":"nbdc-data-sharing-policy-jgap000001","label":{"ja":"NBDC データ共有ポリシー (JGAP000001)","en":"NBDC data sharing policy (JGAP000001)"}}]}]}],"dataVolume":41838112,"fileFormats":[{"code":"txt","label":{"en":"TXT"}},{"code":"pdf","label":{"en":"PDF"}}]}